189100-27-4

Basic information

• Product Name: Benzonitrile, 4-(pyrazinylamino)-
• CAS NO: 189100-27-4
• Molecular Formula: C11H8N4
• Molecular Weight: 196.211
• Mol File: 189100-27-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-(pyrazinylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-(pyrazinylamino)-(189100-27-4)
• EPA Substance Registry System: Benzonitrile, 4-(pyrazinylamino)-(189100-27-4)

Safety Data

• Hazardous Substances Data: 189100-27-4(Hazardous Substances Data)

Upstream product

• 5049-61-6 2-Aminopyrazine 
• 623-00-7 4-bromobenzenecarbonitrile 

Downstream Products

• 319015-47-9 4-[N-(4-hydroxybenzyl)-N-(2-pyrazinyl)amino]benzonitrile 
• 894779-88-5 4-(pyrazin-2-yl)aminobenzylamine 

Relevant articles and documents

Palladium-catalyzed couplings of heteroaryl amines with aryl halides using sodium phenolate as the stoichiometric base

Heteroaryl amines are efficiently coupled (in two hours) to aryl halides with catalytic Pd2(dba)3 and Xantphos to provide the corresponding biaryl amines under microwave and standard thermal conditions. The use of organic-soluble sodium phenolate (NaOPh) as the stoichiometric base promotes facile coupling of a variety of substrates in excellent yields. Georg Thieme Verlag Stuttgart.