189102-20-3

Basic information

• Product Name: 1,3-Dioxolane-4-ethanol, 5,5-diethyl-2,2-dimethyl-, 4-methylbenzenesulfonate, (S)-
• CAS NO: 189102-20-3
• Molecular Formula: C18H28O5S
• Molecular Weight: 356.483
• Mol File: 189102-20-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane-4-ethanol, 5,5-diethyl-2,2-dimethyl-, 4-methylbenzenesulfonate, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane-4-ethanol, 5,5-diethyl-2,2-dimethyl-, 4-methylbenzenesulfonate, (S)-(189102-20-3)
• EPA Substance Registry System: 1,3-Dioxolane-4-ethanol, 5,5-diethyl-2,2-dimethyl-, 4-methylbenzenesulfonate, (S)-(189102-20-3)

Safety Data

• Hazardous Substances Data: 189102-20-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 189102-63-4 (1S,5S)-3-[2-[(1S,3aS,7aS)-1-{(R)-1-[2-((S)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-ethyl}-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-5-hydroxymethyl-4-methylene-cyclohexanol 
• 189102-64-5 (1R,5R)-3-[2-[(1S,3aS,7aS)-1-{(R)-1-[2-((S)-5,5-Diethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethoxy]-ethyl}-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-5-hydroxymethyl-4-methylene-cyclohexanol 

Relevant articles and documents

Antiproliferative hybrid analogs of the hormone 1α,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation

The combination of 10-12 kbar pressure plus Lewis acidic zinc dichloride promotes highly regioselective and stereoselective Diels-Alder cycloaddition between 3-bromo-2-pyrone, prepared in a new way, and unactivated terminal alkene 4-(tert-butyldimethylsiloxy)-1-butene. The conjugate base of A-ring allylic phosphine oxide 20 adds chemospecifically to the C-8 keto group of some C-8,C-24-diketones to form directly metabolically resistant 24-oxo analogs of 1α,25-dihydroxyvitamin D3 (calcitriol). Several of these new hybrid analogs are as efficacious in vitro as calcitriol at inhibiting growth of murine keratinocytes even at physiologically relevant 10-100 nanomolar concentrations.