189119-13-9Relevant academic research and scientific papers
Potent benzimidazolone based human β3-adrenergic receptor agonists
Finley, Don R.,Bell, Michael G.,Borel, Anthony G.,Bloomquist, William E.,Cohen, Marlene L.,Heiman, Mark. L.,Kriauciunas, Aidas,Matthews, Donald P.,Miles, Tania,Neel, David A.,Rito, Christopher J.,Sall, Daniel J.,Shuker, Anthony J.,Stephens, Thomas W.,Tinsley, Frank C.,Winter, Mark A.,Jesudason, Cynthia D.
, p. 5691 - 5694 (2007/10/03)
The synthesis and biological evaluation of a series of benzimidazolone β3 adrenergic receptor agonists are described. A trend toward the reduction of rat atrial tachycardia upon increasing steric bulk at the 3-position of the benzimidazolone mo
SELECTIVE BETA 3 ADRENERGIC AGONISTS
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, (2008/06/13)
The present invention is in the field of medicine, particularly in the treatment of Type II diabetes and obesity. More specifically, the present invention relates to selective β3 adrenergic receptor agonists useful in the treatment of Type II diabetes and obesity. The invention provides compounds and method of treating type II diabetes, comprising administering to a mammal in need thereof compounds of the Formulas I and II: STR1
Selective beta3 adrenergic agonists
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, (2008/06/13)
The present invention is in the field of medicine, particularly in the treatment of Type II diabetes and obesity. More specifically, the present invention relates to selective β3 adrenergic receptor agonists useful in the treatment of Type II diabetes and
