18913-04-7

Basic information

• Product Name: Ethylene glycol monononyl ether
• Synonyms: 2-(nonyloxy)-Ethanol
• CAS NO: 18913-04-7
• Molecular Formula: C₁₁H₂₄O₂
• Molecular Weight: 0
• Mol File: 18913-04-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethylene glycol monononyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: Ethylene glycol monononyl ether(18913-04-7)
• EPA Substance Registry System: Ethylene glycol monononyl ether(18913-04-7)

Safety Data

• Hazardous Substances Data: 18913-04-7(Hazardous Substances Data)

Usage

InChI:InChI=1S/C11H24O2/c1-2-3-4-5-6-7-8-10-13-11-9-12/h12H,2-11H2,1H3

Upstream product

• 4536-30-5 ethylene glycol mono-n-dodecyl ether 
• 107-21-1 ethylene glycol 
• 143-15-7 1-dodecylbromide 
• 143-08-8 nonyl alcohol 
• 693-58-3 1-Bromononane 
• 5432-30-4 2-octyl-1,3-dioxolane 

Downstream Products

• 1245923-31-2 C₂₇H₃₈F₂N₇O₅P 

Relevant articles and documents

Voriconazole derivative, synthesis thereof, and use thereof in long-acting preparation

The invention relates to a compound of formula (I), and a salt, an N-oxide, a quaternary ammonium and a stereoisomer thereof. R to R in the formula (I) are as defined in claims. The invention also relates to an intermediate for preparing the compound of formula (I), and a method for preparing the compound of formula (I). The invention further relates to a use of the compound of formula (I) as a drug especially used for preventing or treating fungal infection.

Synthesis of acyclic quaternary ammonium compounds containing ω-alkoxyethyl and 2-hydroxyethyl substituents at the nitrogen atom

A series of acyclic symmetric quaternary ammonium chlorides Me2(HOCH2CH2)N+(CH2CH2O)nR Cl– (n = 1, R = n-C9H19; n = 2, R = n-C6H13; n = 3, R = n-C3H7) was synthesized by alkylation of the corresponding tertiary amines Me2N(CH2CH2O)nR with ethylene chlorohydrin in a two-phase system, using water as a solvent. The tertiary amines were synthesized in a heterogeneous system organic phase—aqueous phase, using an aqueous solution of Me2NH and a solid alkali. The intermediate monoethers of ethylene, diand triethylene glycol were obtained in high yield via a phase-transfer alkylation in dioxane, using solid KOH. The proton and carbon atom signals in the NMR spectra of the synthesized amines and ammonium chlorides were assigned based on the data of heteronuclear correlations (1H, 13C).

FOSFLUCONAZOLE DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS

The invention relates to a compound of formula (I) and the salts, N-oxides, quaternary amines, and stereoisomers thereof, wherein R1 to R8 are as defined in the claims. The invention further relates to intermediates and methods for the preparation of the compounds of formula (I). The invention also relates to the compounds of formula (I) for use as a medicament, particularly for the prevention or treatment of fungal infections.