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Usage

Uses

Used in Pharmaceutical Industry:
(1S 2S)-N,N'-BIS(3,3-DIMETHYLBUTYL)-1,2-ETHANEDIAMINE is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its unique structure and properties make it a valuable component in the development of new drugs and medications.
Used in Asymmetric Catalysis:
(1S 2S)-N N'-BIS(3 3-DIMETHYLBUTYL)-1 2& is used as a ligand in asymmetric catalysis, a process that is crucial for the production of enantiomerically pure compounds. Its chiral centers play a significant role in the selectivity and efficiency of the catalytic reactions.
Used in Production of Fine Chemicals and Polymers:
(1S 2S)-N,N'-BIS(3,3-DIMETHYLBUTYL)-1,2-ETHANEDIAMINE serves as a precursor in the production of fine chemicals and polymers. Its unique structure allows for the creation of a wide range of high-quality products with specific properties.
Used in Medicine:
Due to its potential applications in medicine, (1S 2S)-N,N'-BIS(3,3-DIMETHYLBUTYL)-1,2-ETHANEDIAMINE can be utilized in the development of new therapeutic agents and treatments for various medical conditions.
Used in Materials Science:
(1S 2S)-N N'-BIS(3 3-DIMETHYLBUTYL)-1 2& has potential applications in materials science, where its unique structure and properties can be harnessed to create innovative materials with specific characteristics for various industries.
Used in Organic Chemistry:
(1S 2S)-N,N'-BIS(3,3-DIMETHYLBUTYL)-1,2-ETHANEDIAMINE is also used in organic chemistry for various research and development purposes, contributing to the advancement of the field.

InChI:InChI=1/C18H38N2/c1-17(2,3)11-13-19-15-9-7-8-10-16(15)20-14-12-18(4,5)6/h15-16,19-20H,7-14H2,1-6H3/t15-,16-/m0/s1

Upstream product

• 1194545-71-5 C₁₈H₃₄N₂ 
• 7065-46-5 3,3-dimethylbutanoic acid chloride 
• 32044-22-7 (1S,2S)-cyclohexane-1,2-diammonium 2,3-dihydroxysuccinate 
• 21436-03-3 (S,S)-1,2-diaminocyclohexane 
• 20439-47-8 (1R,2R)-1,2-diaminocyclohexane 
• 926-36-3 4,4-dimethylpentanal 

Downstream Products

• 1194655-27-0 dimethyl 6,6-dihydroxy-5,5'-dinitrobiphenyl-3,3-dicarboxylate (1R,2R)-N,N-di-(3,3-dimethylbutyl)-1,2-cyclohexanediamine complex 
• 1357292-08-0 C₂₀H₃₈N₂O₂ 
• 644958-86-1 (1S,2S)-(+)-N,N'-bis(3,3-dimethylbutyl)-N,N'-dimethyl-1,2-diaminocyclohexane 

Relevant academic research and scientific papers

The search for an easily-prepared sparteine surrogate

(?)-Sparteine has proven itself to be a highly efficient and versatile ligand. However, in recent years it has become difficult to source. In addition the (+)-enantiomer is also not readily available. Here we report a suite of chiral diamines as potential sparteine surrogates. Chiral trans-1,2-diaminocyclohexane is commercially available in both enantiomeric forms and the parent structure can be easily modified. New (and known) chiral diamines have been tested in the asymmetric silylation of N-Boc pyrrolidine, N-Boc piperidine, the α-alkylation of dimethylhydrazones and in the rearrangement of meso-epoxides. While none match the selectivity of the highly evolved natural product, there is certainly potential for this class of diamine ligands to perform in a diverse set of asymmetric transformations.

Organocatalytic Knoevenagel condensation by chiral: C 2-symmetric tertiary diamines

The efficient Knoevenagel condensation catalyzed by (1S,2S)-1,2-diaminocyclohexane derivatives is presented and investigated. Various aliphatic aldehydes undergo condensation with active methylene compounds to yield the corresponding products in high yields. α-Branched aldehydes were found to be efficiently converted to the corresponding enantiomerically enriched products by using these chiral tertiary diamine catalysts.

Novel chiral bisformamide-promoted asymmetric allylation of benzaldehyde with allyltrichlorosilane

Novel chiral bisformamides have been prepared from (R,R)-1,2- cyclohexanediamine and utilized as Lewis bases in the asymmetric allylation of benzaldehyde with allyltrichlorosilane. The reaction in the presence of Lewis base 1i gave an 83:17 enantiomeric r

Supramolecular-directed chiral induction in biaryl derivatives

(Chemical Equation Presented) A thermodynamically controlled resolution has allowed for the generation of diastereomerically enriched complexes, by chirality transfer from an enantiopure building block to a dynamically racemic biaryl derivative. A switcha