18917-68-5

Basic information

• Product Name: 2,4-diaminoquinazoline-6-carbonitrile
• CAS NO: 18917-68-5
• Molecular Formula: C₉H₇N₅
• Molecular Weight: 185.1854
• Mol File: 18917-68-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 549.1°C at 760 mmHg
• Flash Point: 285.9°C
• Density: 1.46g/cm³
• Vapor Pressure: 4.15E-12mmHg at 25°C
• Refractive Index: 1.75
• CAS DataBase Reference: 2,4-diaminoquinazoline-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-diaminoquinazoline-6-carbonitrile(18917-68-5)
• EPA Substance Registry System: 2,4-diaminoquinazoline-6-carbonitrile(18917-68-5)

Safety Data

• Hazardous Substances Data: 18917-68-5(Hazardous Substances Data)

Usage

General Description

2,4-diaminoquinazoline-6-carbonitrile is a chemical compound with the molecular formula C9H7N5. It is a heterocyclic compound containing two amino groups and a cyano group. 2,4-diaminoquinazoline-6-carbonitrile has potential applications in the field of medicinal chemistry, particularly in the development of anticancer and antiviral drugs. It has been investigated for its ability to inhibit the growth of cancer cells and has shown promise in preclinical studies. Additionally, 2,4-diaminoquinazoline-6-carbonitrile has been studied for its potential to inhibit the replication of certain viruses, making it a potential candidate for the development of antiviral medications. 2,4-diaminoquinazoline-6-carbonitrile's unique structure and reactivity make it an interesting target for further research and development in the pharmaceutical industry.

Upstream product

• 151-50-8 potassium cyanide 
• 13741-90-7 2,4,6-triaminoquinazoline 
• 7154-34-9 2,4-diamino-6-nitroquinazoline 

Downstream Products

• 52128-06-0 6-[(4-Chloro-phenylamino)-methyl]-quinazoline-2,4-diamine; compound with acetic acid 
• 1955-63-1 4-[(2,4-diamino-quinazolin-6-ylmethyl)-amino]-benzoic acid 
• 52128-04-8 6-[(3-Chloro-phenylamino)-methyl]-quinazoline-2,4-diamine; compound with acetic acid 
• 87174-61-6 6-[(2-Chloro-phenylamino)-methyl]-quinazoline-2,4-diamine; compound with acetic acid 
• 52128-08-2 6-[(3,5-Dichloro-phenylamino)-methyl]-quinazoline-2,4-diamine; compound with acetic acid 
• 52128-16-2 6-<<(3,4-dichlorophenyl)amino>methyl>-2,4-quinazolinediamine acetate 
• 52128-20-8 6-<<<4-chloro-3-(trifluoromethyl)phenyl>-amino>methyl>-2,4-quinazolinediamine acetate 
• 52128-10-6 6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-quinazoline-2,4-diamine; compound with acetic acid 
• 52128-18-4 6-[(3-Bromo-phenylamino)-methyl]-quinazoline-2,4-diamine; compound with acetic acid 
• 52128-12-8 6-[(6-Chloro-naphthalen-2-ylamino)-methyl]-quinazoline-2,4-diamine; compound with acetic acid 
• 93502-97-7 (S)-2-{4-[(2,4-Diamino-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid di-tert-butyl ester 
• 27023-77-4 2,4-diamino-quinazoline-6-carboxaldehyde 
• 27133-39-7 6-anilinomethyl-quinazoline-2,4-diamine 
• 207562-23-0 2,4-diaminoquinazoline-6-carboxylic acid 

Relevant articles and documents

Process for synthesizing antifolates

A process for synthesizing antifolate compounds is disclosed. The process includes cyclization of a readily available starting reagent, followed by one or more coupling steps to produce compounds that mimic folic acid. The compounds synthesized have commercial use as drugs in oncology, inflammatory disease, and other medical fields.

Synthesis and enzymatic hydrolysis of esters, constituting simple models of soft drugs

One way to minimise systemic side effects of drugs is to design molecules, soft drugs, in such a way that they are metabolically inactivated rapidly after having acted on their pharmacological target. Hydrolases (esterases, peptidases, lipases, glycosidas