52128-22-0Relevant academic research and scientific papers
Folate Antagonists. 20. Synthesis and Antitumor and Antimalarial Properties of Trimetrexate and Related 6--2,4-quinazolinediamines
Elslager, Edward F.,Johnson, Judith L.,Werbel, Leslie M.
, p. 1753 - 1760 (2007/10/02)
A series of 6--2,4-quinazolinediamines have been prepared by catalytic hydrogenation of the requisite 2,4-diamino-6-quinazolinecarbonitriles in the presence of the appropiate benzenamine.Formylation, acetylation, and nitrosation provide
