18919-58-9

Upstream product

• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 145-13-1 Pregnenolone 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 145-13-1 Pregnenolone 
• 135024-01-0 (20R)-20,25-dihydroxy-26,27-dipropyl-3β-(trimethylsilanyloxy)-cholest-5-en-22-one 
• 135024-05-4 (20R)-26,27-dipropyl-3β,20,25-trihydroxy-cholest-5-en-22-one 
• 139332-39-1 C₅₅H₆₄O₈ 

Relevant academic research and scientific papers

Stereoselective Dehydroxyboration of Allylic Alcohols to Access (E)-Allylboronates by a Combination of C-OH Cleavage and Boron Transfer under Iron Catalysis

Iron-catalyzed direct SN2′ dehydroxyboration of allylic alcohols has been developed to access (E)-stereoselective allylboronates. Allylic alcohols with diverse structures and functional groups, especially derived from natural products, underwent smooth transformation. The six-membered ring transition state formed by allylic alcohols and iron-boron intermediate was indicated to be the key component involved in transfer of the boron group, activation of the C-OH bond, and control of the stereoselectivity.

Carbohydrates as chiral auxiliaries: Synthesis of 2-hydroxy-β-D-glucopyranosides

A new 2-step, 1-pot procedure for the stereoselective glycosylation of allylic alcohols with 1,2-di-O-benzoyl-β-D-glucopyranosides to produce 2-hydroxy-β-D-glucopyranosides has been developed. The required precursor for the glycosylation was readily obtained from tri-O-benzyl-D-glucal in 2 steps (91% overall).