18919-58-9

Basic information

• Product Name: 3β-(Trimethylsilyloxy)pregn-5-en-20-one
• Synonyms: 3β-(Trimethylsilyloxy)pregn-5-en-20-one
• CAS NO: 18919-58-9
• Molecular Formula: C₂₄H₄₀O₂Si
• Molecular Weight: 388.6587
• Mol File: 18919-58-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3β-(Trimethylsilyloxy)pregn-5-en-20-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-(Trimethylsilyloxy)pregn-5-en-20-one(18919-58-9)
• EPA Substance Registry System: 3β-(Trimethylsilyloxy)pregn-5-en-20-one(18919-58-9)

Safety Data

• Hazardous Substances Data: 18919-58-9(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 145-13-1 Pregnenolone 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 

Downstream Products

• 145-13-1 Pregnenolone 
• 135024-01-0 (20R)-20,25-dihydroxy-26,27-dipropyl-3β-(trimethylsilanyloxy)-cholest-5-en-22-one 
• 135024-05-4 (20R)-26,27-dipropyl-3β,20,25-trihydroxy-cholest-5-en-22-one 
• 139332-39-1 C₅₅H₆₄O₈ 

Relevant articles and documents

Stereoselective Dehydroxyboration of Allylic Alcohols to Access (E)-Allylboronates by a Combination of C-OH Cleavage and Boron Transfer under Iron Catalysis

Iron-catalyzed direct SN2′ dehydroxyboration of allylic alcohols has been developed to access (E)-stereoselective allylboronates. Allylic alcohols with diverse structures and functional groups, especially derived from natural products, underwent smooth transformation. The six-membered ring transition state formed by allylic alcohols and iron-boron intermediate was indicated to be the key component involved in transfer of the boron group, activation of the C-OH bond, and control of the stereoselectivity.