18924-67-9

Basic information

• Product Name: 2,2'-(hexadecylimino)bisethanol
• Synonyms: 2,2'-(hexadecylimino)bisethanol;2,2'-(Hexadecylimino)diethanol;3-Hexadecyl-3-azapentane-1,5-diol;N,N-Bis(2-hydroxyethyl)-1-hexadecanamine;2,2'-(hexadecylazanediyl)diethanol;Palmityldiethanolamine;Ethanol,2,2'-(hexadecylimino)bis-
• CAS NO: 18924-67-9
• Molecular Formula: C₂₀H₄₃NO₂
• Molecular Weight: 329.56092
• EINECS: 242-678-2
• Mol File: 18924-67-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 455.4°Cat760mmHg
• Flash Point: 191.4°C
• Appearance: /
• Density: 0.913g/cm³
• CAS DataBase Reference: 2,2'-(hexadecylimino)bisethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-(hexadecylimino)bisethanol(18924-67-9)
• EPA Substance Registry System: 2,2'-(hexadecylimino)bisethanol(18924-67-9)

Safety Data

• Hazardous Substances Data: 18924-67-9(Hazardous Substances Data)

Usage

General Description

2,2'-(hexadecylimino)bisethanol, also known as hexadecyl-bisethanolamine, is an organic chemical compound. It is a long-chain amine alcohol that is commonly used as a surfactant and emulsifier in various industrial and household products. Its main function is to reduce surface tension and allow substances to mix together that would otherwise repel each other, making it ideal for use in cosmetics, detergents, and personal care products. This chemical is also utilized in the fabrication of coatings, adhesives, and lubricants, where it helps to enhance the stability and performance of the final products. Additionally, it has potential applications in the pharmaceutical and agricultural sectors due to its ability to improve the solubility and bioavailability of active ingredients.

Upstream product

• 111-42-2 2,2'-iminobis[ethanol] 
• 112-82-3 hexadecanyl bromide 
• 36653-82-4 1-Hexadecanol 
• 143-27-1 hexadecylamine 
• 107-07-3 2-chloro-ethanol 
• 4860-03-1 1-Chlorohexadecan 

Downstream Products

• 120857-28-5 hexadecyltris(2-hydroxyethyl)ammonium chloride 
• 1179328-74-5 Br^(1-)*C₃₄H₇₂NO₂⁽¹⁺⁾ 
• 1179328-59-6 N-hexadecyl-N-decyldiethanolammonium bromide 
• 1179328-58-5 N-hexadecyl-N-octyldiethanolammonium bromide 
• 1179328-57-4 N-hexadecyl-N-hexyldiethanolammonium bromide 
• 65151-47-5 Hexadecyldihydroxyethylbenzylammonium chloride 
• 60687-82-3 hexadecyl-bis-(2-hydroxy-ethyl)-methyl-ammonium; chloride 

Relevant articles and documents

Modular Strategy to Expand the Chemical Diversity of DNA and Sequence-Controlled Polymers

Sequence-defined polymers with customizable sequences, monodispersity, substantial length, and large chemical diversity are of great interest to mimic the efficiency and selectivity of biopolymers. We report an efficient, facile, and scalable synthetic route to introduce many chemical functionalities, such as amino acids and sugars in nucleic acids and sequence-controlled oligophosphodiesters. Through achiral tertiary amine molecules that are perfectly compatible with automated DNA synthesis, readily available amines or azides can be turned into phosphoramidites in two steps only. Individual attachment yields on nucleic acids and artificial oligophosphodiesters using automated solid-phase synthesis (SPS) were >90% in almost all cases. Using this method, multiple water-soluble sequence-defined oligomers bearing a range of functional groups in precise sequences could be synthesized and purified in high yields. The method described herein significantly expands the library of available functionalities for nucleic acids and sequence-controlled polymers.

Alkynyl quaternary ammonium salt multifunctional surfactants and preparation method thereof

The invention discloses a series of alkynyl quaternary ammonium salt multifunctional surfactants and a preparation method thereof. A structural formula of quaternary ammonium salt is shown in the description, wherein R represents a C4-C22 linear, branched or cycloalkyl, aryl or alkenyl group. The preparation method comprises the following steps: (1) carrying out alkylation on ethanol amine under alkaline and acetonitrile reflux conditions by virtue of bromo-hydrocarbon; and (2) carrying out further alkylation on tertiary amine under an ethanol reflux condition by virtue of propargyl bromide, so as to obtain alkynyl quaternary ammonium salt, namely reddish brown semitransparent viscous liquid or solid. The alkynyl quaternary ammonium salt multifunctional surfactants have very high surface activity, good corrosion resistance and excellent viscoelasticity, the preparation method is simple and feasible, the raw material cost is low, the operation is easy, the yield is high, and the surfactants are environmentally friendly.

Design of new potent and selective secretory phospholipase A2 inhibitors. Part 5: Synthesis and biological activity of 1-alkyl-4-[4,5-dihydro-1,2,4-[4H]-oxadiazol-5-one-3-ylmethylbenz-4′-yl(oyl)] piperazines

Among the different PLA2s identified to date, the group IIA secretory PLA2 (sPLA2 GIIA) is implied in diverse pathological conditions. In this work we describe the synthesis, inhibitory activities, and structure-activity relationships (SAR) of a new class of substituted piperazine derivatives. The in vitro fluorimetric assay using two groups of enzymes, GIB and GIIA, revealed several compounds as highly potent inhibitors (IC50 = 0.1 μM). The in vivo activity assessed by ip or per os administration in a carrageenan-induced edema test in rats showed that two compounds proved to be as potent as indomethacin (10 mg/kg).