18924-67-9

Usage

Uses

Used in Cosmetics Industry:
2,2'-(hexadecylimino)bisethanol is used as a surfactant and emulsifier for its ability to blend ingredients effectively, ensuring the stability and consistency of cosmetic products. It contributes to the formation of smooth textures and even distribution of active ingredients, enhancing the overall performance and user experience.
Used in Detergent and Cleaning Products:
In the detergent industry, 2,2'-(hexadecylimino)bisethanol is utilized as a surfactant to lower the surface tension of water, enabling it to mix with oils and dirt. This property is crucial for the effective removal of stains and grime from various surfaces, making it a valuable component in the formulation of cleaning agents.
Used in Personal Care Products:
2,2'-(hexadecylimino)bisethanol is used as an emulsifying agent in personal care products such as creams, lotions, and shampoos. Its capacity to mix oil and water components ensures that these products have a uniform texture and deliver their active ingredients effectively to the skin or hair.
Used in Coatings, Adhesives, and Lubricants:
2,2'-(hexadecylimino)bisethanol is employed in the fabrication of coatings, adhesives, and lubricants to improve their stability and performance. Its surfactant properties help in the even distribution of components, leading to enhanced adhesion, durability, and lubrication.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,2'-(hexadecylimino)bisethanol is used to improve the solubility and bioavailability of active pharmaceutical ingredients. Its ability to reduce surface tension aids in the dispersion of drugs, ensuring their effective absorption and action within the body.
Used in Agricultural Industry:
2,2'-(hexadecylimino)bisethanol has potential applications in agriculture, where it can be used to enhance the solubility and bioavailability of active ingredients in agrochemicals. This can lead to improved efficacy and reduced environmental impact by minimizing the amount of chemical needed for effective pest control and crop protection.

Upstream product

• 4860-03-1 1-Chlorohexadecan 
• 111-42-2 2,2'-iminobis[ethanol] 
• 143-27-1 hexadecylamine 
• 107-07-3 2-chloro-ethanol 
• 112-82-3 hexadecanyl bromide 
• 36653-82-4 1-Hexadecanol 

Downstream Products

• 60687-82-3 hexadecyl-bis-(2-hydroxy-ethyl)-methyl-ammonium; chloride 
• 120857-28-5 hexadecyltris(2-hydroxyethyl)ammonium chloride 
• 65151-47-5 Hexadecyldihydroxyethylbenzylammonium chloride 
• 1179328-57-4 N-hexadecyl-N-hexyldiethanolammonium bromide 
• 1179328-58-5 N-hexadecyl-N-octyldiethanolammonium bromide 
• 1179328-59-6 N-hexadecyl-N-decyldiethanolammonium bromide 
• 1179328-74-5 Br^(1-)*C₃₄H₇₂NO₂⁽¹⁺⁾ 

Relevant academic research and scientific papers

Modular Strategy to Expand the Chemical Diversity of DNA and Sequence-Controlled Polymers

Sequence-defined polymers with customizable sequences, monodispersity, substantial length, and large chemical diversity are of great interest to mimic the efficiency and selectivity of biopolymers. We report an efficient, facile, and scalable synthetic route to introduce many chemical functionalities, such as amino acids and sugars in nucleic acids and sequence-controlled oligophosphodiesters. Through achiral tertiary amine molecules that are perfectly compatible with automated DNA synthesis, readily available amines or azides can be turned into phosphoramidites in two steps only. Individual attachment yields on nucleic acids and artificial oligophosphodiesters using automated solid-phase synthesis (SPS) were >90% in almost all cases. Using this method, multiple water-soluble sequence-defined oligomers bearing a range of functional groups in precise sequences could be synthesized and purified in high yields. The method described herein significantly expands the library of available functionalities for nucleic acids and sequence-controlled polymers.

COMPOUNDS, COMPOSITONS AND METHODS RELATED TO ANTIMICROBIAL APPLICATIONS

The present disclosure is in the field of polymers and pharmaceuticals/antimicrobials. The disclosure provides compounds based on SNAP (synthetic novel antimicrobial polymer) technology, compositions and methods of managing microbial infections including surgical site infections (SSIs). The present compounds are used as a management/therapeutic strategy to target microbial infections and have advantages including excellent antimicrobial potency, biofilm disruption ability, broad spectrum activity against various organisms covering both gram negative and gram positive bacteria as well as fungal pathogens, and low toxicity profile to ensure a healthy therapeutic window for use in humans.

Alkynyl quaternary ammonium salt multifunctional surfactants and preparation method thereof

The invention discloses a series of alkynyl quaternary ammonium salt multifunctional surfactants and a preparation method thereof. A structural formula of quaternary ammonium salt is shown in the description, wherein R represents a C4-C22 linear, branched or cycloalkyl, aryl or alkenyl group. The preparation method comprises the following steps: (1) carrying out alkylation on ethanol amine under alkaline and acetonitrile reflux conditions by virtue of bromo-hydrocarbon; and (2) carrying out further alkylation on tertiary amine under an ethanol reflux condition by virtue of propargyl bromide, so as to obtain alkynyl quaternary ammonium salt, namely reddish brown semitransparent viscous liquid or solid. The alkynyl quaternary ammonium salt multifunctional surfactants have very high surface activity, good corrosion resistance and excellent viscoelasticity, the preparation method is simple and feasible, the raw material cost is low, the operation is easy, the yield is high, and the surfactants are environmentally friendly.

NANOPARTICLE DRUG DELIVERY SYSTEMS

The invention provides pharmaceutical compositions and method of using the compositions, wherein the compositions comprise liposomes or micelles that contain one or more targeting peptides and/or anticancer drugs. In various embodiments, the components of the liposomes can include a) a phospholipid and optionally a lipid that is not a phospholipid; b) a pegylated lipid; c) a peptide-ethylene glycol (EG)-lipid conjugate wherein the peptide is a targeting ligand, and d) one or more drug-conjugated lipid, encapsulated drugs, or a combination thereof. The peptide- EG-lipid conjugate can be, for example, a compound of Formula (I) or Formula (II). The ethylene glycol (EG) segments of the peptide-EG-lipid conjugate can be, for example, EG6 to about EG36; and the EG segment can be conjugated to one or more lysine moieties.

Design of new potent and selective secretory phospholipase A2 inhibitors. Part 5: Synthesis and biological activity of 1-alkyl-4-[4,5-dihydro-1,2,4-[4H]-oxadiazol-5-one-3-ylmethylbenz-4′-yl(oyl)] piperazines

Among the different PLA2s identified to date, the group IIA secretory PLA2 (sPLA2 GIIA) is implied in diverse pathological conditions. In this work we describe the synthesis, inhibitory activities, and structure-activity relationships (SAR) of a new class of substituted piperazine derivatives. The in vitro fluorimetric assay using two groups of enzymes, GIB and GIIA, revealed several compounds as highly potent inhibitors (IC50 = 0.1 μM). The in vivo activity assessed by ip or per os administration in a carrageenan-induced edema test in rats showed that two compounds proved to be as potent as indomethacin (10 mg/kg).

Low pressure derived mixed phosphorous- and sulfur-containing reaction products useful in power transmitting compositions and process for preparing the same

A phosphorous- and sulfur-containing additive and its use to impart anti-wear and/or antioxidant properties to oleaginous compositions such as fuels and lubricating oils, particularly power transmission compositions, such as automatic transmission fluids, is disclosed. The additive comprises a mixture of products formed by simultaneously reacting (1) a beta-hydroxy thioether, such as thiobisethanol, and (2) a phosphorous-containing reactant, such as tributyl phosphite. The reaction is carried out under reduced pressure conditions (e.g., -40 KPa to -100 KPa) to limit the amount of thioether species in said additive to less than about 45 mole %.