189307-37-7Relevant academic research and scientific papers
Synthesis of 5'-C-hydroxyalkylthymidines and their incorporation into oligodeoxynucleotides
Wang, Guangyi,Middleton, Patrick J.,An, Yi-Zhong
, p. 2393 - 2396 (1997)
5'-C-Hydroxymethyl-, 5'-C-hydroxyethyl, and 5'-C-hydroxypropylthymidine derivatives were prepared through four synthetic routes, which constitute an approach to introduce hydroxyalkyl of different lengths at C5' of thymidine. 5'-C-hydroxymethyl- and 5'-C-hydroxypropylthymidines were converted to the corresponding phosphoramidites and incorporated into oligodeoxynucleotides.
