189330-23-2 Usage
General Description
5-(Difluoromethyl)thiophene-2-carboxylic acid is a chemical compound consisting of a thiophene ring with a carboxylic acid group at position 2 and a difluoromethyl group at position 5. It is often used as a building block in the synthesis of various pharmaceutical compounds and agrochemicals. The difluoromethyl group can enhance the biological activity and metabolic stability of the resulting molecules, making it a valuable tool for drug discovery and development. Additionally, the thiophene core is known for its diverse pharmacological properties, including anti-inflammatory, anticancer, and antimicrobial activities. As a result, 5-(difluoromethyl)thiophene-2-carboxylic acid is an important intermediate in the pharmaceutical and agrochemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 189330-23-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,3,3 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 189330-23:
(8*1)+(7*8)+(6*9)+(5*3)+(4*3)+(3*0)+(2*2)+(1*3)=152
152 % 10 = 2
So 189330-23-2 is a valid CAS Registry Number.
189330-23-2Relevant articles and documents
BENZIMIDAZOLE DERIVATIVES AS ITK INHIBITORS
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Page/Page column 171, (2014/03/25)
The present disclosure is directed to certain inhibitors of kinases such as ITK, BLK, BMX, BTK, JAK3, TEC, TXK, HER2 (ERBB2), or HER4 (ERBB4), in particular ITK, pharmaceutical compositions comprising such compounds, and method of treating diseases mediated by such kinases.