189331-46-2

Basic information

• Product Name: METHYL 3-ETHYLTHIOPHENE-2-CARBOXYLATE
• Synonyms: METHYL 3-ETHYLTHIOPHENE-2-CARBOXYLATE
• CAS NO: 189331-46-2
• Molecular Formula: C8H10O2S
• Molecular Weight: 170.23
• Mol File: 189331-46-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 3-ETHYLTHIOPHENE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-ETHYLTHIOPHENE-2-CARBOXYLATE(189331-46-2)
• EPA Substance Registry System: METHYL 3-ETHYLTHIOPHENE-2-CARBOXYLATE(189331-46-2)

Safety Data

• Hazardous Substances Data: 189331-46-2(Hazardous Substances Data)

Upstream product

• 7311-64-0 3-bromothiophene-2-carboxylic acid 
• 25796-68-3 3-bromo-thiophene-2-carbonyl chloride 
• 26137-08-6 methyl 3-bromothiophene-2-carboxylate 
• 1163277-35-7 methyl 3-vinylthiophene-2-carboxylate 
• 74965-84-7 3-ethyl-2-thiophenecarboxylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 74965-84-7 3-ethyl-2-thiophenecarboxylic acid 

Relevant articles and documents

Photoinduced and Palladium-Catalyzed Remote Desaturation of Amide Derivatives

A photoinduced and palladium-catalyzed remote desaturation of O-acyl hydroxamides to unsaturated amides under mild conditions has been achieved. The formation of the alkyl Pd(II) intermediate by the recombination of alkyl radical and Pd(I) species is critical to achieve this efficient and selective desaturation of alkanes. This reaction features good site-selectivity, is terminal oxidant-free, and produces moderate to excellent yields for a variety of unsaturated amides. Remarkably, this approach enables late-stage desaturation of complex and biologically important molecules.

BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to benzofurane and benzothiophene derivatives of formula (I) Formula (I) wherein (R1)n, R2, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to phenyl derivatives of formula (I) Formula (I) wherein (R1)n, R3, R4a, R4b, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (III) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.