189338-32-7

Usage

Uses

Used in Pharmaceutical Industry:
4-Carboxy-3,5-dichlorobenzotrifluoride is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of highly functionalized molecules with specific biological activities.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Carboxy-3,5-dichlorobenzotrifluoride is employed as an intermediate for the synthesis of pesticides and other agrochemicals. Its properties enable the production of effective and targeted compounds for crop protection and pest management.
Used in Specialty Polymers Production:
4-Carboxy-3,5-dichlorobenzotrifluoride is utilized in the production of specialty polymers, which are high-performance materials with unique properties tailored for specific applications. Its incorporation into polymer structures can enhance their performance characteristics, such as thermal stability, chemical resistance, and mechanical strength.
Used in Organic Synthesis:
As a building block in organic synthesis, 4-Carboxy-3,5-dichlorobenzotrifluoride is employed in the creation of complex organic molecules for various applications. Its versatility allows chemists to design and synthesize novel compounds with specific functionalities and properties, expanding the scope of chemical research and development.

InChI:InChI=1/C8H3Cl2F3O2/c9-4-1-3(8(11,12)13)2-5(10)6(4)7(14)15/h1-2H,(H,14,15)

Upstream product

• 124-38-9 carbon dioxide 
• 54773-20-5 1,3-dichloro-5-(trifluoromethyl)benzene 
• 118754-53-3 2-bromo-1,3-dichloro-5-(trifluoromethyl)benzene 

Relevant academic research and scientific papers

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS

The present invention relates to the use of a compound of formula I wherein R1, R2, R3, R4, X and n are as defined herein or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS

The present invention relates to the use of a compound of general formula (I) wherein R1/R2 are independently from each other hydrogen, lower alkyl, -CH2)o-cycloalkyl for o being 0 or 1, or are benzyl or heterocycloalkyl; or R1 and R2 are together with the N-atom to which they are attached a ring containing -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH2)2-O-(CH2)2-, -(CH2)2-S-(CH2)2-, -(CH2)2-NR-(CH2)2-, -(CH2)2-C(O)-(CH2)2-, -(CH2)2-CF2-(CH2)2-, -CH2-CHR-(CH2)2, -CHR-(CH2)3, CHR-(CH2)2-CHR-, or is the ring 2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester and R is hydroxy, halogen, cycloalkyl, or C(O)O-lower alkyl; X is -(CH2)4-, -(CH2)3-, -(CH2)2- or -CH2-; R3 is S-lower alkyl, CF3, OCHF2, lower alkoxy, lower alkyl, phenyl, cycloalkyl or halogen; R4 is CF3, lower alkoxy, lower alkyl, halogen and n is 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers thereof for the manufacture of a medicament for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.

Metalation and derivatization of all six dichlorobenzotrifluorides: Site selectivities

The metalation of 2,3-, 2,6-, 2,4- and 3,5-dichlorobenzotrifluorides can be readily effected with standard reagents such as lithium diisopropylamide, lithium 2,2,6,6-tetramethylpiperidide, and butyllithium at the chlorine-adjacent 4- and 3-positions and t

Pyrazole derivatives and insecticidal compositions containing the derivative as active component

A pyrazole derivative represented by the formula (1) is low in toxicity and persistence and yet has an extremely high insecticidal efficacy STR1 wherein A is CH, N or C-halogen atom, R1 is hydrogen atom, lower alkyl, lower haloalkyl, benzyl or