1893397-65-3Relevant academic research and scientific papers
METHODS FOR EVALUATING TUMOR CELL SPHEROIDS USING 3D MICROFLUIDIC CELL CULTURE DEVICE
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Page/Page column 54; 55, (2018/10/25)
Provided herein are methods for evaluating tumor cell spheroids in a three-dimensional microfluidic device by determining changes in the relative levels of live cells and dead cells in aliquots cultured under different conditions. Methods described herein allow ex vivo recapitulation of the tumor microenvironment such that the in vivo effectiveness of a test compound in treating tumor tissue may be predicted.
TANK-BINDING KINASE INHIBITOR COMPOUNDS
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, (2016/05/02)
Compounds having the following formula (I) and methods of their use and preparation are disclosed:
