18934-60-6

Upstream product

• 13649-97-3 (S)-4-benzyl-2-methyl-4H-oxazol-5-one 
• 60-34-4 methylhydrazine 
• 3618-96-0 (S)-N-acetylphenylalanine 
• 2018-61-3 (S)-2-acetylamino-3-phenylpropanoic acid 

Relevant academic research and scientific papers

Azapeptides as inhibitors and active site titrants for cysteine proteinases

Ester and amide derivatives of α-azaglycine (carbazic acid, H2NHCOOH), α-azaalanine, and α-azaphenylalanine (i.e., AC-L-Phe-NHN(R)CO-X, where X = H, CH3, or CH2Ph, respectively) were synthesized and evaluated as inhibitors

Cysteine protease inhibition by azapeptide esters

Papain, a prototype cysteine protease, was inhibited in a time-dependent manner by azapeptide esters designed to deliver an azaglycine group to the active-site thiol. For example, the rate of inhibition was 18 M-1 s-1 for Ac-L-PheAgl