189340-63-4

Basic information

• Product Name: 4-[3-methyl-5-(3-trifluoromethyl-benzenesulfonyloxy)-phenoxymethyl]-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 189340-63-4
• Molecular Weight: 529.578
• Mol File: 189340-63-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[3-methyl-5-(3-trifluoromethyl-benzenesulfonyloxy)-phenoxymethyl]-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-methyl-5-(3-trifluoromethyl-benzenesulfonyloxy)-phenoxymethyl]-piperidine-1-carboxylic acid tert-butyl ester(189340-63-4)
• EPA Substance Registry System: 4-[3-methyl-5-(3-trifluoromethyl-benzenesulfonyloxy)-phenoxymethyl]-piperidine-1-carboxylic acid tert-butyl ester(189340-63-4)

Safety Data

• Hazardous Substances Data: 189340-63-4(Hazardous Substances Data)

Upstream product

• 123855-51-6 tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 498-94-2 isonipecotic acid 
• 504-15-4 orcinol 
• 161975-39-9 tert-butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate 
• 189340-61-2 3-trifluoromethylbenzenesulfonic acid 3-hydroxy-5-methylphenyl ester 

Relevant articles and documents

Structure-activity and crystallographic analysis of a new class of non- amide-based thrombin inhibitor

The structure-activity relationships of a novel series of non-amide- based thrombin inhibitors are described. Exploration of the P2 and the aryl binding region for this series has identified optimal groups for achieving nanomolar potency. The binding modes of these optimal groups have been confirmed by X-ray structural analysis.