189362-41-2

Basic information

• Product Name: (S)-Hydroxy-phenyl-acetic acid (1R,2R)-2-cyclopropylamino-cyclohexyl ester
• Synonyms: (S)-Hydroxy-phenyl-acetic acid (1R,2R)-2-cyclopropylamino-cyclohexyl ester
• CAS NO: 189362-41-2
• Molecular Weight: 289.375
• Mol File: 189362-41-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-Hydroxy-phenyl-acetic acid (1R,2R)-2-cyclopropylamino-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-Hydroxy-phenyl-acetic acid (1R,2R)-2-cyclopropylamino-cyclohexyl ester(189362-41-2)
• EPA Substance Registry System: (S)-Hydroxy-phenyl-acetic acid (1R,2R)-2-cyclopropylamino-cyclohexyl ester(189362-41-2)

Safety Data

• Hazardous Substances Data: 189362-41-2(Hazardous Substances Data)

Upstream product

• 17199-29-0 (S)-Mandelic acid 
• 286-20-4 cyclohexane-1,2-epoxide 

Downstream Products

• 189362-43-4 (1R,2R)-2-(cyclopropylamino)cyclohexan-1-ol 

Relevant articles and documents

2(1H)-Quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activities

In order to search for anti-arteriostenotic agents, a series of 2(1H)- quinolinone derivatives was synthesized and evaluated for anti-thrombotic activity and for anti-hyperplastic activity. From this series, (-)-6-[3-[3- cyclopropyl-3-[(1R,2R)-2-hydroxycycyclohexyl]ureido]propoxy]-2(1H)- quinolinone (1p, OPC-33509) was selected as the best candidate by balancing the efficacy on anti-thrombosis and anti-hyperplasia.