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189373-41-9

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  • 4-(N,N-Dimethylaminosulfonyl)-7-(2-aminoethylamino)-2,1,3-benzoxadiazole

    Cas No: 189373-41-9

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189373-41-9 Usage

Uses

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a new precolumn fluorescence derivatization reagent.

Check Digit Verification of cas no

The CAS Registry Mumber 189373-41-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,3,7 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 189373-41:
(8*1)+(7*8)+(6*9)+(5*3)+(4*7)+(3*3)+(2*4)+(1*1)=179
179 % 10 = 9
So 189373-41-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H15N5O3S/c1-15(2)19(16,17)8-4-3-7(12-6-5-11)9-10(8)14-18-13-9/h3-4,12H,5-6,11H2,1-2H3

189373-41-9 Well-known Company Product Price

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  • (93088)  4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan  for HPLC derivatization, ≥99.0% (HPLC)

  • 189373-41-9

  • 93088-25MG-F

  • 1,359.54CNY

  • Detail

189373-41-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-(2-aminoethylamino)-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide

1.2 Other means of identification

Product number -
Other names DBD-ED [=4-(N,N-Dimethylaminosulfonyl)-7-(2-aminoethylamino)-2,1,3-benzoxadiazole]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:189373-41-9 SDS

189373-41-9Downstream Products

189373-41-9Relevant articles and documents

Multiplexing sensory molecules map protons near micellar membranes

Uchiyama, Seiichi,Iwai, Kaoru,De Silva, A. Prasanna

, p. 4667 - 4669 (2008)

(Figure Presented) Hi-fi mapping: Multiplexing fluorescent sensors that simultaneously target proton concentration and polarity move to micellar nanospaces, self-regulate their positions, and report their pKa values and wavelengths, which are c

Environment-sensitive turn-on fluorescent probes for p53-MDM2 protein-protein interaction

Liu, Tingting,Jiang, Yan,Liu, Zhenzhen,Li, Jin,Fang, Kun,Zhuang, Chunlin,Du, Lupei,Fang, Hao,Sheng, Chunquan,Li, Minyong

supporting information, p. 1668 - 1672 (2017/08/22)

A series of probes with a turn-on switch for the p53-MDM2 protein-protein interaction were developed. After careful evaluation, these small molecule fluorescent probes exhibited high practical activity and selectivity in vitro and in cellulo. In particular probe 10, which had a Ki value of 0.03 μM, displayed much better binding affinity compared to the positive control Nutlin-3, which had a Ki value of 0.23 μM. These no-wash environment-sensitive turn-on fluorescent probes have been successfully applied to imaging p53-MDM2 interaction in the human lung cancer cell line A549 (wild-type p53) at the micromolar level. Therefore, these fluorescent probes are expected to be used in drug screening and cell staining in p53-MDM2 fields, as well as in pathological and physiological studies of the p53-MDM2 interaction.

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