18944-66-6Relevant academic research and scientific papers
Lipase-mediated stereoselective transformations of chiral organophosphorus P-boranes revisited: Revision of the absolute configuration of alkoxy(hydroxymethyl)phenylphosphine P-boranes
Kwiatkowska, Malgorzata,Krasinski, Grzegorz,Cypryk, Marek,Cierpial, Tomasz,Kielbasinski, Piotr
, p. 1581 - 1590 (2011/12/15)
The lipase-promoted kinetic resolution of a series of alkoxy(hydroxymethyl) phenylphosphine P-boranes proceeded with moderate stereoselectivity to give both the unreacted substrates and their O-acetyl derivatives. The absolute configurations of the produc
PHOSPHORORGANISCHE VERBINDUNGEN 119. DIE ASYMMETRISCHE INDUKTION ALS MECHANISTISCHER WEGWEISER BEI DER VERESTERUNG VON METHYLPHENYLPHOSPHINSAEURE-HALOGENIDEN UND PSEUDOHALOGENIDEN IN GEGENWART OPTISCH AKTIVER AMINE
Weidert, Peter J.,Geyer, Ekkehard,Horner, Leopold
, p. 255 - 260 (2007/10/02)
The reaction of rac. methylphenylphosphinicacid-halides and pseudohalides MePhP(O)X (X = F, Cl, CN, OC6H4NO2(p)) with alcohols ROH (R = Me, PhCH2, CF3CH2 and i-Prop) leads in the presence of the optically active amines 1-5 to partial optically active esters.The optical induction is between 1 and 14 percent.A mechanism inclidung five- and six bonded phosphorus intermediates is proposed.Key words: Chiral phosphinic acid halides; chiral phosphinicesters; optical induction; optically active amines as inductors; esterification; mechanism
Stereochemistry at the Phosphorus Atom during Palladium-catalysed Formation of Carbon-Phosphorus Bonds and Mechanistic Implications
Xu, Yuanyao,Zhang, Jing
, p. 1606 (2007/10/02)
The reaction of (R)-(+)-isopropyl methylphosphinate (5) with bromobenzene in the presence of Pd(0) catalyst and triethylamine to afford (S)-(-)-isopropyl methylphenylphosphinate (6) proceeds with complete retention of configuration via a front-sided attack by phenylpalladium bromide on the phosphorus nucleophile.
