189452-99-1

Basic information

• Product Name: N-bis[(ethoxycarbonyl)methyl]-4-chloro-N'-[morpholino(thiocarbonyl)]benzamidine
• CAS NO: 189452-99-1
• Molecular Weight: 441.936
• Mol File: 189452-99-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-bis[(ethoxycarbonyl)methyl]-4-chloro-N'-[morpholino(thiocarbonyl)]benzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-bis[(ethoxycarbonyl)methyl]-4-chloro-N'-[morpholino(thiocarbonyl)]benzamidine(189452-99-1)
• EPA Substance Registry System: N-bis[(ethoxycarbonyl)methyl]-4-chloro-N'-[morpholino(thiocarbonyl)]benzamidine(189452-99-1)

Safety Data

• Hazardous Substances Data: 189452-99-1(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 6829-40-9 aminomalonic acid diethyl ester 
• 34840-50-1 4-morpholine 

Relevant articles and documents

Versatile novel syntheses of imidazoles

A novel ring transformation/desulfurization of substituted 2-methyl-1,2,4-thiadiazolium salts 2 provides a versatile entry to imidazoles 3 with a variety of substituents. Simple one-pot procedures combine the preparation of starting 1,2,4-thiadiazolium salts 2 from N-(thiocarbonyl)-N'-methylamidines 1 or 1,2,4-dithiazolium triiodides 6 with the ring transformation/desulfurization to the imidazoles 3. Alternatively, N-(thiocarbonyl)-N'-methylamidines 1 can be transformed to imidazoles 3 or to 1-substituted imidazoles 5 via S-methylation and elimination of methylthiol. In the same manner, a new entry to 4H-imidazoles 8 could be developed.