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18951-35-4

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18951-35-4 Usage

General Description

Corynomycolic acid is a complex lipid molecule found in the cell wall of certain bacterial species, specifically the Corynebacterium genus. It is composed of long-chain fatty acids and mycolic acids, which give the cell wall its characteristic waxy structure and are important for protecting the bacterium from environmental stresses. Corynomycolic acid has been studied for its potential as a biomarker for tuberculosis infection, as well as its role in the pathogenicity and virulence of Corynebacterium species. Additionally, it has been investigated for its potential use in developing new antibiotics and antimicrobial agents to combat bacterial infections. Overall, corynomycolic acid is an important chemical compound with implications for both diagnostic and therapeutic applications in the field of microbiology and infectious diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 18951-35-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,5 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18951-35:
(7*1)+(6*8)+(5*9)+(4*5)+(3*1)+(2*3)+(1*5)=134
134 % 10 = 4
So 18951-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C32H64O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31(33)30(32(34)35)28-26-24-22-20-18-16-14-12-10-8-6-4-2/h30-31,33H,3-29H2,1-2H3,(H,34,35)/t30-,31-/m1/s1

18951-35-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3R)-3-hydroxy-2-tetradecyloctadecanoic acid

1.2 Other means of identification

Product number -
Other names 3-Hydroxy-2-tetradecyloctadecanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18951-35-4 SDS

18951-35-4Related news

Contribution of high-performance liquid chromatography to the identification of some Corynebacterium species by comparison of their corynomycolic acid (cas 18951-35-4) patterns07/19/2019

Reverse-phase high-performance liquid chromatography of corynomycolic acids provided a specific pattern for each Corynebacterium species studied. These data suggest that a fast and reproducible procedure is now available for bacteriological identification at the genus and at the species level of...detailed

Essential Role of Trehalose in the Synthesis and Subsequent Metabolism of corynomycolic acid (cas 18951-35-4) in Corynebacterium matruchotii07/18/2019

A previous paper indicated that corynomycolates synthesized by the fluffy layer fraction prepared from Corynebacterium matruchotii cells appeared exclusively as α-trehalose 6-monocorynomycolate (TMM) (T. Shimakata, K. Tsubokura, T. Kusaka, and K. Shizukuishi, 1985, Arch. Biochem. Biophys. 238, ...detailed

18951-35-4Relevant articles and documents

Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle

Van Der Peet,Gunawan, Christian,Torigoe, Shota,Yamasaki, Sho,Williams, Spencer J.

, p. 5100 - 5103 (2015)

An enantioselective synthesis of (+)-corynomycolic acid, and its elaboration to esters of trehalose, glucose and glycerol, is described. Trehalose dicorynomycolate and trehalose monocorynomycolate activate human and mouse Mincle as effectively as trehalose dicorynomycolate (cord factor). Glucose monomycolate is revealed to be a potent activator of both mouse and human Mincle. Glycerol monocorynomycolate signals through human Mincle, with the activity predominantly residing in the 2′S-isomer.

Enantioselective Hydrogenation of β-Keto Esters using Chiral Diphosphine-Ruthenium Complexes: Optimization for Academic and Industrial Purposes and Synthetic Applications

Ratovelomanana-Vidal,Girard,Touati,Tranchier,Ben Hassine,Genet

, p. 261 - 274 (2007/10/03)

Enantioselective hydrogenation using chiral complexes between atropisomeric diphosphines and ruthenium is a powerful tool for producing chiral compounds. Using a simple and straightforward in situ catalyst preparation, the conditions were optimized using molecular hydrogen for both academic and industrial purposes. This led to the best conditions and the lowest catalytic ratio required for the pressure used. Hydrogenation of various β-keto esters was efficiently performed at atmospheric and higher pressures, leading to the use of very low catalyst-substrate ratios up to 1/20,000. Asymmetric hydrogenations were used in key-steps towards the total synthesis of corynomycolic acid, Duloxetine and Fluoxetine.

Trehalose derivatives

-

, (2008/06/13)

A trehalose derivative of the formula: STR1 wherein one, two, three or four of R1, R2, R3, R4, R5, R6, R7 and R8 are independently selected from the group consisting o

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