18956-18-8 Usage
Uses
Used in Pharmaceutical Industry:
DIHYDROOROXYLIN is used as an antitubercular agent for its ability to inhibit the growth and progression of tuberculosis. Its effectiveness against this disease is attributed to its unique chemical structure, which allows it to target and disrupt the biological processes of the tuberculosis-causing bacteria.
Used in Antiviral Applications:
In addition to its antitubercular properties, DIHYDROOROXYLIN is also used as an antiviral agent. It has been reported to act as an inhibitor of AMV (Avian Myeloblastosis Virus) and HIV reverse transcriptase (RT), which are essential enzymes for the replication of these viruses. By inhibiting these enzymes, DIHYDROOROXYLIN can potentially slow down or prevent the spread of viral infections, making it a valuable tool in the development of antiviral therapies.
Used in Drug Development:
Given its antitubercular and antiviral activities, DIHYDROOROXYLIN can be further explored and developed as a potential therapeutic agent for various diseases. Researchers can investigate its potential synergistic effects when combined with other drugs, as well as its ability to enhance the efficacy of existing treatments. This may lead to the development of novel drug delivery systems or combination therapies that can improve patient outcomes and address drug resistance issues.
Check Digit Verification of cas no
The CAS Registry Mumber 18956-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,5 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18956-18:
(7*1)+(6*8)+(5*9)+(4*5)+(3*6)+(2*1)+(1*8)=148
148 % 10 = 8
So 18956-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H14O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-6,8,12,18-19H,7H2,1H3/t12-/m0/s1
18956-18-8Relevant academic research and scientific papers
A new domino oxidation—rearrangement of 2,3-dihydrowogonin to negletein
Spoerlein-Guettler, Cornelia,Milius, Wolfgang,Obenauf, Johannes,Schobert, Rainer
, p. 1560 - 1562 (2018/03/29)
We report an expeditious, iodine-catalysed oxidation of 2,3-dihydrowogonin to negletein which comprises a Wessely–Moser rearrangement (WMR), associated not with an O-demethylation, as usual, but with an oxygen to oxygen methyl shift. In contrast, DDQ in 1
