18956-18-8 Usage
Uses
(S)-5,7-Dihydroxy-6-methoxy-2-phenylchroman-4-one is reported to be a natural flavonoid derivative as AMV and HIV reverse transcriptase (RT) inhibitors.
Definition
ChEBI: A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 6. Isolated from Pisonia aculeata, it exhibits antitubercular activity.
Check Digit Verification of cas no
The CAS Registry Mumber 18956-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,5 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18956-18:
(7*1)+(6*8)+(5*9)+(4*5)+(3*6)+(2*1)+(1*8)=148
148 % 10 = 8
So 18956-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H14O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-6,8,12,18-19H,7H2,1H3/t12-/m0/s1
18956-18-8Relevant articles and documents
A new domino oxidation—rearrangement of 2,3-dihydrowogonin to negletein
Spoerlein-Guettler, Cornelia,Milius, Wolfgang,Obenauf, Johannes,Schobert, Rainer
, p. 1560 - 1562 (2018/03/29)
We report an expeditious, iodine-catalysed oxidation of 2,3-dihydrowogonin to negletein which comprises a Wessely–Moser rearrangement (WMR), associated not with an O-demethylation, as usual, but with an oxygen to oxygen methyl shift. In contrast, DDQ in 1