487-71-8 Usage
General Description
2-Methoxy-benzene-1,3,5-triol, also known as gentisic acid, is a chemical compound found in some plants such as gentian root and in fruits like strawberries. It is a phenolic compound with antioxidant properties, which means it can help protect cells and tissues in the body from damage caused by free radicals. It has also been studied for its potential anti-inflammatory and anti-cancer properties. Gentisic acid has a variety of uses in the pharmaceutical and food industries, including as a flavoring agent and as a potential ingredient in skincare products due to its antioxidant and anti-inflammatory properties.
Check Digit Verification of cas no
The CAS Registry Mumber 487-71-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 487-71:
(5*4)+(4*8)+(3*7)+(2*7)+(1*1)=88
88 % 10 = 8
So 487-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H8O4/c1-11-7-5(9)2-4(8)3-6(7)10/h2-3,8-10H,1H3
487-71-8Relevant articles and documents
Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene Kinase Pim-1
Chao, Shi-Wei,Su, Ming-Yuan,Chiou, Lih-Chu,Chen, Liang-Chieh,Chang, Chung-I,Huang, Wei-Jan
, p. 1969 - 1976 (2015/09/08)
(Figure Presented). A new method is applied to synthesize hispidulin, a natural flavone with a broad spectrum of biological activities. Hispidulin exhibits inhibitory activity against the oncogenic protein kinase Pim-1. Crystallographic analysis of Pim-1 bound to hispidulin reveals a binding mode distinct from that of quercetin, suggesting that the binding potency of flavonoids is determined by their hydrogen-bonding interactions with the hinge region of the kinase. Overall, this work may facilitate construction of a library of hispidulin-derived compounds for investigating the structure-activity relationship of flavone-based Pim-1 inhibitors.
Synthesis of isoflavones. V. Irigenin and tectorigenin.
Baker,Downing,Floyd,Gilbert,Ollis
, p. 1219 - 1223 (2007/10/08)
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