189563-95-9Relevant academic research and scientific papers
First total synthesis of Mer-N5075A and a diastereomeric mixture of α and β-MAPI, new HIV-I protease inhibitors from a species of Streptomyces
Konda, Yaeko,Takahashi, Yukihiro,Arima, Shiho,Sato, Noriko,Takeda, Kazuyoshi,Dobashi, Kazuyuki,Baba, Masanori,Harigaya, Yoshihiro
, p. 4311 - 4321 (2007/10/03)
Mer-N5075A (1) and α-MAPI and β-MAPI (2 and 3) produced from a species of Streptomyces are new anomalous tetrapeptides having potential HIV-I protease inhibitory activity. The first total synthesis of 1 and a diastereomeric mixture of 2 and 3 was achieved
First total synthesis of Mer-N5075A, a new HIV-I protease inhibitor from Streptomyces chromofuscus
Konda, Yaeko,Takahashi, Yukihiro,Mita, Hiroka,Takeda, Kazuyoshi,Harigaya, Yoshihiro
, p. 345 - 346 (2007/10/03)
The first total synthesis of Mer-N5075A (1), a new potential HIV-I protease inhibitor produced from Streptomyces chromofuscus, was achieved. The synthetic method is available for Mer-N5075A analogues such as α-MAPI (2), GE20372 A (4) and other chemically
