189744-30-7Relevant academic research and scientific papers
Modulation of melphalan resistance in glioma cells with a peripheral benzodiazepine receptor ligand-melphalan conjugate
Kupczyk-Subotkowska, Lidia,Siahaan, Teruna J.,Basile, Anthony S.,Friedman, Henry S.,Higgins, Patricia E.,Song, Di,Gallo, James M.
, p. 1726 - 1730 (1997)
Peripheral benzodiazepine receptors (PBRs) are located on the outer membrane of mitochondria, and their density is increased in brain tumors. Thus, they may serve as a unique intracellular and selective target for antineoplastic agents. A PBR ligand-melph
Diazepam hapten, diazepam artificial antigen, and preparation method and application thereof
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Paragraph 0026; 0028; 0030, (2020/08/25)
The invention discloses a diazepam hapten, a diazepam artificial antigen as well as a preparation method and application thereof. The diazepam artificial antigen provided by the invention is an antigen obtained by coupling the diazepam hapten shown as a formula I with a carrier protein. The diazepam artificial antigen provided by the invention is simple in synthesis method, high in purity and highin yield, and has important value in preparation of diazepam antibodies and detection of diazepam drug residues.
