18975-51-4

Basic information

• Product Name: diphenyl(N,N-diethylaminomethyl)phosphine oxide
• Synonyms: diphenyl(N,N-diethylaminomethyl)phosphine oxide
• CAS NO: 18975-51-4
• Molecular Weight: 287.342
• Mol File: 18975-51-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: diphenyl(N,N-diethylaminomethyl)phosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: diphenyl(N,N-diethylaminomethyl)phosphine oxide(18975-51-4)
• EPA Substance Registry System: diphenyl(N,N-diethylaminomethyl)phosphine oxide(18975-51-4)

Safety Data

• Hazardous Substances Data: 18975-51-4(Hazardous Substances Data)

Upstream product

• 2071-27-4 <(diethylamino)methyl>diphenylphosphine 
• 2037-00-5 N-Hydroxymethyldiethylamine-acetate 
• 1636-15-3 (diethylamino)diphenylphosphine 
• 102-53-4 bis-(diethylamino)methane 
• 1352709-73-9 (diphenylphosphoryl)(N,N-dimethylamino)chloromethane 
• 1079-66-9 chloro-diphenylphosphine 
• 4410-92-8 N,N'-diethylmethanediamine 
• 1101-41-3 Tetraphenyldiphosphin 
• 13125-61-6 N-(chloromethyl)diethylamine 

Relevant articles and documents

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Ambident reactivity of chloro(dialkylamino)-(diphenylphosphinoyl)methanes

The chemical properties of chloro(dialkylamino)(diphenylphosphinoyl) methanes have been studied using the simplest compound of this series, chloro(dimethylamino)(diphenylphosphinoyl)methane, as an example. Chloro- (dimethylamino)(diphenylphosphinoyl)methane shows ambident reactivity when reacting with electrophiles and nucleophiles depending on coreactant nature, it behaves as either electrophilic substrate or phosphorus nucleophile. This fact can be explained by its dissociation in solutions with both C-Cl bond cleavage to give (dimethylamino)- (diphenylphosphinoyl)methyl cation and Cl- anion and C-P bond cleavage to form chloro(dimethylamino)methyl cation and diphenylphosphinite anion. The capability of chloro(dimethylamino) (diphenylphosphinoyl)methane to produce spontaneously Ph2PO-anion allows us to recommend application in organic and organophosphorus synthesis as a synthetic equivalent (synthon) of diphenylphosphinite anion.

DUAL REACTIVITY OF DIPHENYLPHOSPHINOUS AND PHENYLPHOSPHONOUS ACID AMIDES IN REACTIONS WITH N-ACETOXYMETHYL-SUBSTITUTED DIETHYLAMINE, BENZAMIDE, AND ACETAMIDE

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