1352709-73-9Relevant academic research and scientific papers
Ambident reactivity of chloro(dialkylamino)-(diphenylphosphinoyl)methanes
Morgalyuk, Vasilii Petrovich,Strelkova, Tat'Yana Vladimirovna,Nifant'Ev, Eduard Eugenievich
experimental part, p. 93 - 100 (2012/03/07)
The chemical properties of chloro(dialkylamino)(diphenylphosphinoyl) methanes have been studied using the simplest compound of this series, chloro(dimethylamino)(diphenylphosphinoyl)methane, as an example. Chloro- (dimethylamino)(diphenylphosphinoyl)methane shows ambident reactivity when reacting with electrophiles and nucleophiles depending on coreactant nature, it behaves as either electrophilic substrate or phosphorus nucleophile. This fact can be explained by its dissociation in solutions with both C-Cl bond cleavage to give (dimethylamino)- (diphenylphosphinoyl)methyl cation and Cl- anion and C-P bond cleavage to form chloro(dimethylamino)methyl cation and diphenylphosphinite anion. The capability of chloro(dimethylamino) (diphenylphosphinoyl)methane to produce spontaneously Ph2PO-anion allows us to recommend application in organic and organophosphorus synthesis as a synthetic equivalent (synthon) of diphenylphosphinite anion.
Synthesis of polyfunctionalized methylphosphine oxides
Morgalyuk,Strelkova,Nifant'Ev
, p. 380 - 385 (2013/06/05)
N,N-Dialkylamino(diphenylphosphoryl)chloromethanes, a new type of organophosphorus compounds, were synthesized. On dissolving in polar and low polar solvents, N,N-dialkylamino(diphenylphosphoryl)chloromethanes dissociate spontaneously with the P - C bond cleavage to form the diphenylphosphinite anion Ph2PO-. This was confirmed by the reaction of N,N-dimethylamino(diphenylphosphoryl)chloromethane with electrophilic substrates to form the corresponding addition or substitution products of Ph 2PO-. The capability of spontaneous generating the diphenylphosphinite anion considers accessible N,N- dimethylamino(diphenylphosphoryl)chloromethane as a synthetic equivalent of the diphenylphosphinite anion.
A scheme of the stepwise reaction of diphenylchlorophosphine with N,N-dialkylformamides in the presence of NaI
Morgalyuk,Strelkova
experimental part, p. 2096 - 2101 (2012/03/12)
On an example of DMF was proposed and experimentally verified stepwise reaction scheme of the reaction of diphenylchlorophosphine with N,N-dialkylformamides. The first stage is autocatalytic reaction of the synthesis of (diphenylphosphoryl)(N,N-dialkylami
