189757-31-1Relevant academic research and scientific papers
3-amino-2(1H)-quinolones by cyclization of N-acylated anthranilic acid derivatives
Rehwald, Matthias,Gewald, Karl,Lankau, Hans-Joachim,Unverferth, Klaus
, p. 483 - 492 (1997)
Reaction of secondary amines with the N-(iodoacetyl)anthranilic acid derivatives, 2-(iodoacetylamino)acetophenone and 2-(iodoacetylamino)benzophenone yields 3-amino-2(1H)-quinolones in two steps. Analogously heterocondensed 5-amino-6(7H)-pyrazolo[5,4-b]pyridoues were prepared. Hydroxyquinolines were subjected to Cl/OH exchange to give chloroquinolines, which are convenient for consecutive reactions.
