189757-41-3

Upstream product

• 110-91-8 morpholine 
• 189757-40-2 5-(iodo-acetylamino)-1,3-diphenyl-1H-pyrazol-4-carbonitrile 
• 189757-39-9 5-(chloroacetylamino)-1,3-diphenyl-1H-pyrazol-4-carbonitrile 
• 5515-31-1 5-amino-1,3-diphenylpyrazole-4-carbonitrile 

Relevant academic research and scientific papers

3-amino-2(1H)-quinolones by cyclization of N-acylated anthranilic acid derivatives

Reaction of secondary amines with the N-(iodoacetyl)anthranilic acid derivatives, 2-(iodoacetylamino)acetophenone and 2-(iodoacetylamino)benzophenone yields 3-amino-2(1H)-quinolones in two steps. Analogously heterocondensed 5-amino-6(7H)-pyrazolo[5,4-b]pyridoues were prepared. Hydroxyquinolines were subjected to Cl/OH exchange to give chloroquinolines, which are convenient for consecutive reactions.