5515-31-1Relevant academic research and scientific papers
CuCl3: As an efficient catalyst for the preparation of 5-amino-1H-pyrazole-4-carbonitriles by anomeric based oxidation
Khazaei, Ardeshir,Moosavi-Zare, Ahmad Reza,Goudarzi, Hadis,Tavasoli, Mahsa
, p. 87 - 93 (2021/11/09)
3-Methyl-1-sulfonic acid imidazolium trichlorido copper (II) {[Msim]CuCl3} was prepared and used as a new catalyst for the preparation of 5-amino-1H-pyrazole-4-carbonitriles. In this reaction, the pyrazole ring was formed by an anomeric and vinylogous ano
Preparation method of 5-amino-4-cyano-1,3-diphenyl pyrazole
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Paragraph 0023-0044, (2021/05/01)
The invention discloses a preparation method of 5-amino-4-cyano-1,3-diphenyl pyrazole. The method comprises the following steps: putting malononitrile, benzaldehyde, phenylhydrazine and a magnetic silica gel supported ionic liquid catalyst into a reaction flask, and carrying out a stirring reaction at 20-60 DEG C for 0.5-10 hours by using ethanol as a solvent so as to obtain the target product 5-amino-4-cyano-1,3-diphenyl pyrazole by a one-pot method. According to the invention, the catalyst is efficient and high in selectivity, is easy to recycle and can be well recycled multiple times; and the reaction process is simple to operate, mild in condition, environment-friendly and beneficial to large-scale industrial production.
Core-shell structured magnetite silica-supported hexatungstate: A novel and powerful nanocatalyst for the synthesis of biologically active pyrazole derivatives
Nemati, Ramin,Elhamifar, Dawood,Zarnegaryan, Ali,Shaker, Masoumeh
, (2021/09/06)
This article describes the synthesis of a novel core-shell structured magnetic silica-supported hexatungstate (Fe3O4@SiO2-NH3[W6O19]) nanocatalyst through immobilization of hexatungstate on
One-pot synthesis of multicomponent pyrazole-4-carbonitrile derivatives under solvent-free condition by using engineered polyvinyl alcohol catalyst
Patki, Abhijeet S.,Patil, Komal N.,Kusuma, Suman,Muley, Dnyanoba B.,Jadhav, Arvind H.
, p. 2751 - 2773 (2021/04/09)
Heterocyclic chemistry has fascinated the researchers owing to its wide range of applications in various chemical fields. With this perspective, herein we present an environmentally benign procedure for the synthesis of pyrazole and its derivatives throug
The synthesis of 5-amino-1H-pyrazole-4-carbonitriles by anomeric based oxidative aromatization over [CSPy]ZnCl3 as a new catalyst
Moosavi-Zare, Ahmad Reza,Rezaei-Gohar, Mohammad,Tavasoli, Mahsa,Goudarziafshar, Hamid
, p. 2689 - 2700 (2021/03/24)
4-Carboxy-1-sulfopyridin-1-ium monozinc(II) trichloride {[4CSPy]ZnCl3} as a new acidic catalyst was designed and tested on the synthesis of 5-amino-1H-pyrazole-4-carbonitriles by anomeric based oxidative aromatization. The structure of [4CSPy]Z
Superparamagnetic Fe3O4@Alginate supported L-arginine as a powerful hybrid inorganic–organic nanocatalyst for the one-pot synthesis of pyrazole derivatives
Amirnejat, Sara,Nosrati, Aliakbar,Javanshir, Shahrzad
, (2020/08/10)
Hybrid inorganic–organic material Fe3O4@Alg@CPTMS@Arg, was prepared by the layer-by-layer techniques through grafting l-arginine (l-arg) to Fe3O4@Alg using 3-chloropropyltrimethoxysilane (CPTMS) as a linker. Fe
Sodium toluene-4-sulfonate as a reusable and ecofriendly catalyst for greener synthesis of 5-aminopyrazole-4-carbonitrile in aqueous medium
Sapkal, Aboli,Kamble, Santosh
, p. 3597 - 3604 (2020/08/06)
In these environmentally conscious days there is need to use eco-friendly greener technologies, such as solvent free, microwave, ultrasound and use of room temperature. Here report an efficient and green protocol for the synthesis of 5-aminopyrazole-4-carbonitrile from three component condensation of phenyl hydrazine, aldehyde, and malononitrile using NaPTS as catalyst in aqueous medium. Use of water has emerged as a versatile solvent for organic reaction; it is readily available, inexpensive, environmentally benign, neutral and natural solvent. Multicomponent reactions in water are of outstanding value in organic synthesis and green chemistry. The significant features of this article are short reaction time, provide excellent yield, removal of toxic solvent and use of water as green solvent.
Water-mediated ceric ammonium nitrate catalyzed C-C/C-N bond formation: Convenient access to polyfunctionalized pyrazoles via multicomponent reaction
Kadu, Vikas D.,Hublikar, Mahesh G.,Raut, Dattatraya G.,Bhosale, Raghunath B.
, p. 1189 - 1194 (2019/04/05)
An efficient multicomponent approach has been developed in the environmentally green aqueous medium for synthesis of substituted polyfunctionalized pyrazoles. The simple and readily available aldehydes, malononitrile and phenylhydrazines substrates afford
Facile one-pot synthesis of 5-amino-1H-pyrazole-4-carbonitriles using alumina–silica-supported MnO2 as recyclable catalyst in water
Poonam,Singh, Ram
, p. 4531 - 4542 (2019/05/15)
A novel, facile, one-pot, multicomponent protocol for the synthesis of 5-amino-1H-pyrazole-4-carbonitrile derivatives has been developed using alumina–silica-supported MnO2 as recyclable catalyst in water and sodium dodecyl benzene sulphonate a
