189809-76-5Relevant articles and documents
Two carbon homologation of carboxylic acids using acrylamide as a radical trap
Barton, Derek H.R.,Liu, Wansheng
, p. 2431 - 2434 (2007/10/03)
Photolysis of O-acyl derivatives of N-hydroxy-2-thiopyridone in the presence of acrylamide in dichloromethane furnished crystalline 2-(pyridine-2-thiyl)-carboxamides. Desulfurization of the latter by nickel boride afforded primary amides in excellent yields.
The invention of radical reactions. Part XXXVIII. Homologation of carboxylic acids with acrylamide and synthetic studies of 3-deoxy-D-arabino-2-heptulosonic acid (DAH) and its 4-epimer
Barton, Derek H. R.,Liu, Wansheng
, p. 12067 - 12088 (2007/10/03)
Alkyl radicals generated from O-acyl derivatives of N-hydroxy-2-thiopyridone added onto acrylamide at room temperature to form crystalline 2-(2-pyridylsulfanyl)-carbosamides. Desulfurization of the latter by nickel boride at roam temperature afforded primary amides in quantitative yield. 3-Deoxy-D-arabino-2-heptulosonic acid (DAH), its 4-epimer, and their derivatives were effectively synthesized from commercial D-ribonolactone by similar radical chemistry.