189810-94-4

Basic information

• Product Name: 2,4-Diamino-5-Iodo-6-Methylpyrimidine
• Synonyms: 2,4-Diamino-5-Iodo-6-Methylpyrimidine;5-Iodo-6-methylpyrimidine-2,4-diamine
• CAS NO: 189810-94-4
• Molecular Formula: C₅H₇IN₄
• Molecular Weight: 250.04035
• Mol File: 189810-94-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 150～152℃
• Appearance: /
• CAS DataBase Reference: 2,4-Diamino-5-Iodo-6-Methylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Diamino-5-Iodo-6-Methylpyrimidine(189810-94-4)
• EPA Substance Registry System: 2,4-Diamino-5-Iodo-6-Methylpyrimidine(189810-94-4)

Safety Data

• Hazardous Substances Data: 189810-94-4(Hazardous Substances Data)

Usage

General Description

2,4-Diamino-5-Iodo-6-Methylpyrimidine, also known as DIAIMP, is a chemical compound with the molecular formula C6H7N5I. It is a pyrimidine derivative, which is a six-membered ring organic compound that contains nitrogen and carbon atoms. DIAIMP is a potent antihypertensive agent and has been studied for its potential use in treating cardiovascular diseases. It also has antibacterial properties and is being explored for its potential as an antimicrobial agent. DIAIMP is a valuable chemical compound with diverse potential applications in the fields of medicine and pharmaceuticals.

Upstream product

• 5600-21-5 2-amino-6-methyl-4-chloropyrimidine 
• 1791-73-7 6-methylpyrimidine-2,4-diamine 

Downstream Products

• 189810-00-2 2-amino-5-{2-[1-(4-chlorophenyl)cyclopentyl]vinyl}-6-methyl-4-pyrimidinylamine 
• 1073643-02-3 2,4-diamino-5-[3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine 
• 1073643-21-6 2,4-diamino-5-[(S)-3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine 
• 1073643-19-2 2,4-diamino-5-[(R)-3-(3-methoxy-5-phenylphenyl)but-1-ynyl]-6-methylpyrimidine 
• 1088496-60-9 2,4-diamino-5-[3-(2,5-dimethoxyphenyl)prop-1-ynyl]-6-methylpyrimidine 
• 207799-45-9 2,4-diamino-6-methyl-5-[3-(4-chlorophenyl)-3-oxo-1-propynyl]pyrimidine 
• 189810-11-5 2,4-diamino-6-methyl-5-(3-phenyl-1-propynyl)pyrimidine 
• 1053056-77-1 2,4-diamino-6-methyl-5-[3-(4-chlorophenyl)-3-methyl-1-butenyl]pyrimidine 
• 189810-18-2 2,4-DIAMINO-6-METHYL-5-[3-(4-FLUORO PHENYL)-3-METHYL-1-BUTENYL]PYRIMIDINE 
• 189810-32-0 2,4-diamino-6-methyl-5-[3-(4-trifluoromethylphenyl)-3-methyl-1-butynyl]pyrimidine 

Relevant articles and documents

Inhibitors of dihydrofolate reductase: Design, synthesis and antimicrobial activities of 2,4-diamino-6-methyl-5-ethynylpyrimidines

Novel 2,4-diamino-6-methyl-5-ethynylpyrimidines were prepared via palladium catalyzed coupling of 2,4-diamino-5-iodo-6-methyl-pyrimidine with terminal acetylenes. The compounds were inhibitors of dihydrofolate reductase and showed in vitro activity agains

Inhibitors of Dihydrofolate Reductase With Antibacterial Antiprotozoal, Antifungal and Anticancer Properties

The compositions and methods described herein discloses the design, synthesis and testing of compounds that act as inhibitors of DHFR. The basic scaffold of these inhibitors includes a 2,4-diaminopyrimidine ring with a propargyl linker to another substitu

5[W(substituted aryl)alkenylene and alkynylene]-2,4-diaminopyrimidines as pesticides

5-Substituted-2,4-diaminopyrimidines, and agriculturally acceptable salts thereof, when present in insecticidally or acaricidally effective amounts, and with a suitable agricultural carrier, are useful as active ingredients in novel insecticidal and acaricidal compositions. These pyrimidines may be represented by the following formula: STR1 wherein Ar is STR2 and wherein U is an alkenylene or alkynylene moiety, and R, R1, R2, R3, R4, V, W, X, Y, Z and n are as defined herein; also disclosed and claimed are novel intermediates thereof.