18982-43-9Relevant articles and documents
Substrate promiscuity of ortho-naphthoquinone catalyst: Catalytic aerobic amine oxidation protocols to deaminative cross-coupling and n-nitrosation
Kim, Hun Young,Oh, Kyungsoo,Si, Tengda
, p. 9216 - 9221 (2019/10/08)
ortho-Naphthoquinone-based organocatalysts have been identified as versatile aerobic oxidation catalysts. Primary amines were readily cross-coupled with primary nitroalkanes via deaminative pathway to give nitroalkene derivatives in good to excellent yields. Secondary and tertiary amines were inert to ortho-naphthoquinone catalysts; however, secondary nitroalkanes were readily converted by ortho-naphthoquinone catalysts to the corresponding nitrite species that in situ oxidized the amines to the corresponding N-nitroso compounds. Without using harsh oxidants in a stoichiometric amount, the present catalytic aerobic oxidation protocol utilizes the substrate promiscuity feature to provide a facile access to amine oxidation products under mild reaction conditions.
An efficient solventless synthesis of α-aryl-N-[1-methyl-2-(2/4- chlorophenyl)] ethyl nitrones and their antimicrobial activity
Amutha, Chinnadurai,Saravanan, Sivaperuman,Dhandapani, Perundurai Subramaniam,Muthusubramanian, Shanmugam,Sivasubramanian, Shanmugaperumal
, p. 276 - 282 (2008/09/20)
An efficient solventless synthesis of α-aryl-N-[1-methyl-2-(2/4- chlorophenyl)]ethyl nitrones has been achieved in excellent yield. The compounds are characterized by NMR and X-ray studies. The antimicrobial activities of the synthesized compounds have al
