189870-31-3Relevant academic research and scientific papers
Rate acceleration of the Baylis-Hillman reaction in polar solvents (water and formamide). Dominant role of hydrogen bonding, not hydrophobic effects, is implicated
Aggarwal, Varinder K.,Dean, David K.,Mereu, Andrea,Williams, Richard
, p. 510 - 514 (2007/10/03)
A substantial acceleration of the Baylis-Hillman reaction between cyclohexenone and benzaldehyde has been observed when the reaction is conducted in water. Several different amine catalysts were tested, and as with reactions conducted in the absence of so
Superior amine catalysts for the Baylis-Hillman reaction: The use of DBU and its implications
Aggarwal, Varinder K.,Mereu, Andrea
, p. 2311 - 2312 (2007/10/03)
DBU, which is normally regarded as a hindered and non-nucleophilic base, is in fact the optimum catalyst for the Baylis-Hillman reaction, providing adducts at much faster rates than using DABCO or 3HQD; the scope of the Baylis-Hillman reaction is enhanced
Ketalised α- and β-lithiated α,β-unsaturated ketones: New masked acylvinyl anion equivalents
Bachki, Abderrazak,Foubelo, Francisco,Yus, Miguel
, p. 4921 - 4934 (2007/10/03)
The reaction of chloroketals 1, 5 and 10 with an excess of lithium powder and a catalytic amount of DTBB (4-5%) in THF at -78 or -90°C leads to the corresponding functionalised organolithium compounds 2, 6 and 11, respectively, resulting from a chlorine/l
