18989-74-7Relevant academic research and scientific papers
Nickel catalyzed site selective C-H functionalization of α-aryl-thioamides
Bandyopadhyay, Debashruti,Thirupathi, Annaram,Dhage, Nagsen Munjaji,Mohanta, Nirmala,Peruncheralathan
, p. 6405 - 6409 (2018)
A catalytic site selective intramolecular C-S bond forming reaction is demonstrated for the first time. The C-H bond functionalization of α-aryl-thioacetanilides was efficiently catalyzed by 2 mol% NiBr2, resulting in valuable 2-aminobenzo[b]thiophenes in moderate to good yields. Furthermore, the selective sp2 C-H bond functionalization over sp3 is exemplified.
