189951-29-9

Upstream product

• 7471-26-3 N-(4-methoxyphenyl)benzenesulphonamide 
• 106-96-7 propargyl bromide 
• 98-09-9 benzenesulfonyl chloride 
• 104-94-9 4-methoxy-aniline 

Relevant academic research and scientific papers

Rhodium-catalyzed intramolecular hydroarylation of 1-halo-1-alkynes: Regioselective synthesis of semihydrogenated aromatic heterocycles

The regioselective intramolecular hydroarylation of (3-halo-2-propynyl) anilines, (3-halo-2-propynyl) aryl ethers, or (4-halo-3-butynyl) aryl ethers was efficiently catalyzed by Rh2(OCOCF3)4 to give semihydrogenated aromatic heterocycles, such as 4-halo-1,2-dihydroquinolines, 4-halo-3-chromenes, or 4-(halomethylene)chromans, in good to excellent yields. Some synthetic applications taking advantage of the halo-substituents of the products are also illustrated. Ring a rhodium! Regioselective intramolecular hydroarylation of haloacetylenes efficiently catalyzed by [Rh 2(tfa)4] (see scheme; tfa=OCOCF3) gave semihydrogenated aromatic heterocycles in good to excellent yields. Copyright

Synthesis of N,N-bispropargylanilines via Eglinton coupling - The potential acyclic molecular tweezers

The synthesis of title compounds 3a-g from N-cyano- and N-benzenesulfonyl-N-propargyl anilines (2a-g) via Cu(OAc)2 mediated Eglinton coupling reaction is described.