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Usage

Uses

Used in Organic Synthesis:
Cyclopropyl(3-phenyloxiran-2-yl)methanone is utilized as a key intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, cyclopropyl(3-phenyloxiran-2-yl)methanone serves as a building block for the development of new drugs. Its specific structural features can be leveraged to design molecules with targeted therapeutic effects, potentially leading to the discovery of novel treatments for a range of diseases and conditions.
Used in Materials Science:
Cyclopropyl(3-phenyloxiran-2-yl)methanone also finds application in materials science, where it can be used to develop new materials with unique properties. Its incorporation into polymers or other materials can lead to the creation of advanced materials with improved characteristics, such as enhanced stability, reactivity, or selectivity, depending on the desired application.

Upstream product

• 63261-41-6 (E)-1-cyclopropyl-3-phenylpropen-1-one 
• 100-42-5 styrene 
• 1312775-34-0 3-(tert-butylperoxy)-1-cyclopropyl-3-phenylpropan-1-one 

Relevant academic research and scientific papers

Iron-catalyzed carbonylation-peroxidation of alkenes with aldehydes and hydroperoxides

A three-component reaction of alkenes, aldehydes, and hydroperoxides catalyzed by FeCl2 to β-peroxy ketones has been achieved. This three-component reaction can be also applied to the synthesis of α-carbonyl epoxides, through either a stepwise base-induced epoxidation of the separated β-peroxy ketone products or a one-pot process by simply adding base to the reaction mixture after the completion of the three-component reaction.

Scoping the triphasic/PTC conditions for the Juliá-Colonna epoxidation reaction

A new, highly efficient procedure for the Juliá-Colonna epoxidation is reported. Based on the original triphasic protocol it is shown that the co-catalysis of the reaction with phase transfer catalysts results in a dramatic increase of reactivity and some

Development of the Julia asymmetric epoxidation reaction. Part 2. Application of the oxidation to alkyl enones, enediones and unsaturated keto esters

Polyleucine-based systems have been used to catalyse the asymmetric oxidation of a variety of alkyl enones 1-4, 9-14, an enynone 16 and a dienone 17 to afford the corresponding epoxides 5-8, 18-26 in good to excellent yield and optical purity. A range of enediones 30-32, 34 and one unsaturated keto ester 33 have also been epoxidised stereoselectively to afford optically active epoxides 35-39. The epoxidations were carried out with basic peroxide as the oxidant; the polyleucine catalyst was prepared from leucine N-carboxyanhydride using 1,3-diaminopropane, water (employing a humidity cabinet) or a polystyrene immobilised amine as the initiator. Preliminary mass spectral data on material derived from L-leucine and 1,3-diaminopropane (DAP-PLL) suggest that the catalyst consists of material that contains 22 ± 10 leucine residues.

Unexpected asymmetric epoxidation reactions catalysed by polyleucine-based systems

Polyleucine-based systems have been shown to catalyse the asymmetric epoxidation of a variety of enones, an enynone, selected enediones and an unsaturated ketoester.