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3-Benzoyl-5,22-diene-24-ethyl-cholesterol is a complex organic compound derived from cholesterol, a naturally occurring steroid found in the body. 3-benzoyl-5,22-diene-24-ethyl-cholesterol is characterized by the presence of a benzoyl group attached to the 3-position, a double bond between the 5 and 22 carbon atoms, and an ethyl group at the 24-position. The structure of this molecule is significant in the context of steroid chemistry, as it represents a modified form of cholesterol with potential applications in pharmaceuticals, chemical research, and the synthesis of other steroidal compounds. The specific arrangement of functional groups in 3-benzoyl-5,22-diene-24-ethyl-cholesterol can influence its chemical properties and reactivity, making it a subject of interest for scientists studying the structure-activity relationships of steroidal molecules.

1900-50-1

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1900-50-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1900-50-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,0 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1900-50:
(6*1)+(5*9)+(4*0)+(3*0)+(2*5)+(1*0)=61
61 % 10 = 1
So 1900-50-1 is a valid CAS Registry Number.

1900-50-1Relevant academic research and scientific papers

Synthesis and cytotoxicity of new stigmasterol derivatives

Lu, Yu,Hu, Jizhi,Wu, Zibin,Zeng, Li,Yu, Bo

, p. 715 - 721 (2018/07/15)

This study identifies potential antitumor compounds from a series of new stigmasterol derivatives. Eleven stigmasterol derivatives were synthesized and their structures were confirmed by 1H NMR, MS, and elemental analyses. Their cytotoxicity in vitro against three human cancer cell lines (MCF-7, A549 and HepG2) were evaluated by the MTT assay. Among these compounds, AB-5 and AB-11 shows much better cytotoxicity against MCF-7, A549, and HepG2 cells, and AB-10 exhibits selective cytotoxicity against MCF-7. Their structure-activity relationships were also investigated. In conclusion, AB-5, AB-10 and AB-11 serve as potential compounds for the new generation of anticancer drugs.

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