190012-08-9

Usage

Chemical structure

Contains a spiro ring system with a 1,4-dioxane and azaspirodecane moiety, and a 4-methoxybenzoyl group attached to the spiro ring.

Functional groups

1,4-dioxane, azaspirodecane, and 4-methoxybenzoyl.

Application

Used in various organic synthesis reactions and pharmaceutical research.

Potential use

Development of new drugs and materials due to its unique structure and functional groups.

Safety concerns

Proper handling and careful research are necessary due to the potential hazardous nature of certain chemical compounds.

Upstream product

• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 
• 177-11-7 4,4-ethylenedioxy-piperidine 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 5056-80-4 (+/-)-sendaverine 
• 91586-44-6 7-Acetyl-6-methoxy-2-(4-methoxybenzoyl)-1,2,3,4-tetrahydroisoquinoline 
• 91586-29-7 Methyl 6-methoxy-2-(4-methoxybenzoyl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylate 
• 91586-46-8 6-Methoxy-2-(4-methoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-7-carbonyl chloride 
• 91586-45-7 6-Methoxy-2-(4-methoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-7-carboxylic acid 
• 91586-27-5 6-(4-Methoxy-benzoyl)-2-oxo-5,6,7,8-tetrahydro-2H-pyrano[3,2-c]pyridine-3-carboxylic acid methyl ester 
• 91586-47-9 7-Acetoxy-6-methoxy-2-(4-methoxybenzoyl)-1,2,3,4-tetrahydroisoquinoline 
• 91586-26-4 1-(4-methoxybenzoyl)piperidin-4-one 

Relevant academic research and scientific papers

Inverse Electron Demand Diels-Alder Reactions of 3-Carbomethoxy-2-pyrones. Controlled Introduction of Oxygenated Aromatics: Benzene, Phenol, Catechol, Resorcinol, and Pyrogallol Annulation. Regiospecific Total Synthesis of Sendaverine and a Preparation of 6,7-Benzomorphans

A full investigation of the preparation and Diels-Alder reactions of 3-carbomethoxy-2-pyrones is described.Methods for the preparation of a full range of oxygen-substituted aromatics: benzene, 1-, 2-, or 3-phenol, symmetrical or unsymmetrical o-catechol, resorcinol, and pyrogallol annulation from a common 3-carbomethoxy-2-pyrone intermediate are detailed.A regiospecific total synthesis of sendaverine, a 2-benzyltetrahydroisoquinoline possessing a selectively protected, symmetrical o-catechol, and a preparation of 6,7-benzomorphans are described.

Double carbonylation of aryl iodides with amines under an atmospheric pressure of carbon monoxide using sulfur-modified Au-supported palladium

A double carbonylation of aryl iodides with amines proceeded smoothly under an atmospheric pressure of carbon monoxide by using palladium nanoparticles (Pd NPs) leached from a sulfur-modified Au-supported palladium material (SAPd), producing α-ketoamides in good to excellent yields. This journal is