190064-28-9 Usage
Uses
Used in Pharmaceutical Industry:
PNU-99,194 is used as a therapeutic agent for the treatment of anxiety disorders. As a selective 5-HT1A receptor agonist, it modulates the serotonin system, which plays a crucial role in regulating mood and anxiety levels. Its agonistic action on the 5-HT1A receptor helps alleviate anxiety symptoms and improve overall mental well-being.
Used in Neurology:
PNU-99,194 is used as a potential treatment for depression. 5-(3 4-(DIMETHOXY)PHENYL)-1 3-'s interaction with the 5-HT1A receptor has been shown to have antidepressant effects, providing relief from depressive symptoms and improving mood regulation.
Used in Cognitive Enhancement:
PNU-99,194 is used as a cognitive enhancer to improve cognitive function in individuals with cognitive dysfunction. Its agonistic action on the 5-HT1A receptor has been linked to enhanced cognitive performance, memory, and learning abilities.
Used in Neurodegenerative Disorders:
PNU-99,194 is used as a potential treatment for neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. Its agonistic effects on the 5-HT1A receptor have shown promise in modulating neurobehavioral responses and slowing down the progression of neurodegenerative conditions.
Used in Research and Development:
PNU-99,194 is used as a research tool in the development of new therapeutic agents targeting the serotonin system. Its selective agonistic action on the 5-HT1A receptor makes it a valuable compound for studying the role of serotonin in various mental health and neurological conditions, paving the way for the discovery of novel treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 190064-28-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,0,6 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 190064-28:
(8*1)+(7*9)+(6*0)+(5*0)+(4*6)+(3*4)+(2*2)+(1*8)=119
119 % 10 = 9
So 190064-28-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H16O4/c1-17-13-4-3-9(7-14(13)18-2)10-5-11(15)8-12(16)6-10/h3-4,7,10H,5-6,8H2,1-2H3
190064-28-9Relevant academic research and scientific papers
Phenylethanolamine compounds useful as beta 3 agonists, process for producing the same, and intermediates in the production of the same
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, (2008/06/13)
PCT No. PCT/JP96/03097 Sec. 371 Date Apr. 24, 1998 Sec. 102(e) Date Apr. 24, 1998 PCT Filed Oct. 24, 1996 PCT Pub. No. WO97/15549 PCT Pub. Date May 1, 1997The present invention relates to phenylethanolamine compounds represented by general formula [I]: (where R1 represents hydrogen or halogen; R2 represents hydrogen, hydroxy, lower alkoxy, lower alkoxy substituted with one or two lower alkoxycarbonyl or carboxy groups, lower alkoxy substituted with lower alkylaminocarbonyl which may be substituted with lower alkoxy, lower alkoxy substituted with cyclic aminocarbonyl of 4 to 6 carbon atoms, lower alkoxycarbonyl or carboxy; R3 represents hydrogen, hydroxy, lower alkoxy or lower alkoxy substituted with one or two lower alkoxycarbonyl or carboxy groups; R2 and R3 may be bonded to each other to form methylenedioxy substituted with carboxy or lower alkoxycarbonyl; and m and n are 0 or 1), and their pharmacologically acceptable salts, which have a potent beta 3 adrenergic stimulating effect and high beta 3 adrenergic receptor selectivity, as well as to processes for their production and intermediates in their production.
