190078-92-3

Basic information

• Product Name: 3-Cyclobutene-1,2-dione,3-(dimethylamino)-4-methoxy-(9CI)
• Synonyms: 3-Cyclobutene-1,2-dione,3-(dimethylamino)-4-methoxy-(9CI)
• CAS NO: 190078-92-3
• Molecular Formula: C7H9NO3
• Molecular Weight: 155.15126
• Product Categories: METHOXY
• Mol File: 190078-92-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Cyclobutene-1,2-dione,3-(dimethylamino)-4-methoxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclobutene-1,2-dione,3-(dimethylamino)-4-methoxy-(9CI)(190078-92-3)
• EPA Substance Registry System: 3-Cyclobutene-1,2-dione,3-(dimethylamino)-4-methoxy-(9CI)(190078-92-3)

Safety Data

• Hazardous Substances Data: 190078-92-3(Hazardous Substances Data)

Upstream product

• 506-59-2 N,N-dimethylammonium chloride 
• 5222-73-1 3,4-dimethoxy-3-cyclobutene-1,2-dione 
• 124-40-3 dimethyl amine 

Downstream Products

• 19230-34-3 3,4-bis(dimethylamino)-3-cyclobutene-1,2-dione 

Relevant articles and documents

A new mode of cyclobutenedione ring opening for the synthesis of 2-oxobut-3-enamides and tetrasubstituted furans

A dichotomy between the additions of organolithiums and lithium amides to cyclobutenediones is described wherein the former give carbonyl addition products while the latter induce ring opening by enone cleavagevia O- toC-lithium transfer. This distinct mode of ring scission gives access to 2-oxobut-3-enamides and tetrasubstituted furans.

COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS

The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.