19009-63-3Relevant academic research and scientific papers
Catalytic dehydrogenative dual functionalization of ethers: Dealkylation-oxidation-bromination accompanied by C-O bond cleavage: Via aerobic oxidation of bromide
Moriyama, Katsuhiko,Hamada, Tsukasa,Nakamura, Yu,Togo, Hideo
, p. 6565 - 6568 (2017/07/10)
Catalytic dehydrogenative dual functionalization (DDF) of ethers via oxidation, dealkylation, and α-bromination by the aerobic oxidation of bromide was developed to obtain the corresponding α-bromo ketones in high yields. In particular, the reaction of substituted tetrahydrofurans as cyclic ethers provided 3,3-dibromo tetrahydrofuran-2-ols in high yields selectively through the double α-bromination.
Ring Opening of Aryl Cyclopropyl Ketones to 1-Acyl-1,1,3-tribromopropanes and Their Cyclization to 2-Aryl-3,3-dibromo-2-methoxy and -2-cyanotetrahydrofurans
Takahashi, Masahiko,Takeshi, Noriaki,Myojoh, Kohji,Sano, Hideyuki,Morisawa, Toshio
, p. 209 - 211 (2007/10/02)
The reaction of aryl cyclopropyl ketones 1 with excess bromine gave 1-acyl-1,1,3-tribromopropanes 2, which were cyclized to 2-aryl-3,3-dibromo-2-methoxytetrahydrofurans 3 on treatment with alkaline in aqueous methanol. 2-Aryl-3,3-dibromo-2-cyanotetrahydro
