190202-08-5

Upstream product

• 4885-02-3 Dichloromethyl methyl ether 
• 190202-21-2 3,5-Dimethyl-6-methylsulfanyl-2-phenyl-2H-[1,2]thiazine 1,1-dioxide 
• 117076-71-8 3,5-Dimethyl-1,1-dioxo-2-phenyl-6-rhodano-1,2-thiazin 

Downstream Products

• 220966-75-6 4-methyl-3-methylthio-2,2-dioxo-1-phenyl-1H-thieno<3,4-c><1,2>thiazine 
• 229491-97-8 4-(2-ethoxycarbonyl-2-cyanovinyl)-3,5-dimethyl-6-methylthio-1,1-dioxo-2-phenyl-2H-1,2-thiazine 
• 220966-83-6 4-methyl-3-methylsulfinyl-2,2-dioxo-1-phenyl-1H-thieno<3,4-c><1,2>thiazine 
• 220966-77-8 7-formyl-4-methyl-3-methylthio-2,2-dioxo-1-phenyl-1H-thieno<3,4-c><1,2>thiazine 

Relevant academic research and scientific papers

4-(1-methyl-2-sulfamoylvinyl)pyrazoles by ring transformation of 1,1-dioxo-2H-1,2-thiazine-4-carbaldehydes with hydrazines

As masked 1,3-dicarbonyl compounds, 1,1-dioxo-2H-1,2-thiazine-4-carbaldehydes (2a-e, 7) undergo ring transformations with nucleophilic hydrazines to produce 4-[1-methyl-2-(arylsulfamoyl)vinyl]pyrazoles (9a-i). For 9h, an X-ray structural analysis is reported. With less nucleophilic semicarbazide and p-nitrophenylhydrazine the hydrazones (11a,b) were isolated. The carbaldehydes 2a-e, 7 and 8a,b were synthesized by formylation of the 1,1-dioxo-2H-1,2-thiazines 1a-e, 5 and 6a,b with dichloromethyl methyl ether/ TiCl4. In the case of 1a-e mixtures of 4- and 6-carbaldehydes (2a-e/3a-e) were obtained, which, however, could be used for the synthesis of pyrazoles. Johann Ambrosius Barth 1997.