19023-66-6Relevant articles and documents
Reactivity of phosphonium diylids with esters and amides
Cristau, Henri-Jean,Ribeill, Yves
, p. C51 - C53 (2007/10/02)
The phosphonium diylid (C6H5)2P(CH2)(CH2Li) reacts readily with various esters and amides to give acylated phosphonium salts and Wittig products.In the case of N,N-dimethylbenzamide the reaction can be directed mainly to the Wittig products by protonation.Depending on the nature of the carbonyl group, unexpected reactions, such as conjugate additions to α,β-unsaturated compounds or enolization of α-hydrogenated amides, can also take place.