190256-76-9Relevant academic research and scientific papers
Enantioselective Protonation of Silyl Enol Ethers Catalyzed by a Chiral Pentacarboxycyclopentadiene-Based Bronsted Acid
An, Shaoyu,Li, Jun,Li, Pingfan,Yuan, Chao
, p. 1317 - 1320 (2019/06/19)
The enantioselective protonation of silyl enol ethers was realized in the presence of a pentacarboxycyclopenta-1,3-diene-based chiral Bronsted acid catalyst with water as an achiral proton source to give the corresponding α-aryl ketones in good yields and up to 75percent ee.
Development of a new Lewis base-tolerant chiral LBA and its application to catalytic asymmetric protonation reaction
Cheon, Cheol Hong,Imahori, Tatsushi,Yamamoto, Hisashi
supporting information; experimental part, p. 6980 - 6982 (2010/11/02)
A new Lewis base-tolerant LBA (Lewis Acid Assisted Bronsted Acid) derived from La(OTf)3 and (S)-HOP has been developed as a new chiral Bronsted acid. This acid has been successfully applied as a catalyst to asymmetric protonation reactions of silyl enol ethers of 2-substituted cyclic ketones.
