1903-65-7

Basic information

• Product Name: N-ETHYLPIPERIDINE-4-CARBOXAMIDE
• Synonyms: N-ETHYLPIPERIDINE-4-CARBOXAMIDE;N-ETHYL-4-PIPERIDINECARBOXAMIDE
• CAS NO: 1903-65-7
• Molecular Formula: C₈H₁₆N₂O
• Molecular Weight: 156.23
• Mol File: 1903-65-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-ETHYLPIPERIDINE-4-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ETHYLPIPERIDINE-4-CARBOXAMIDE(1903-65-7)
• EPA Substance Registry System: N-ETHYLPIPERIDINE-4-CARBOXAMIDE(1903-65-7)

Safety Data

• Hazardous Substances Data: 1903-65-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 513, 1986 DOI: 10.1021/jo00354a021

Upstream product

• 39178-35-3 isonicotinoyl chloride hydrochloride 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 41116-48-7 N-ethyl-4-pyridinecarboxamide 
• 1016716-42-9 1-Boc-4-(ethylcarbamoyl)piperidine 

Relevant articles and documents

Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8)

Activation of CCR8 by its ligand CCL1 may play an important role in diseases such as asthma, multiple sclerosis, and cancer. The study of small molecule CCR8 antagonists will help establish the validation of these hypotheses. We report the design, synthesis, and progress toward optimization of potent small molecule CCR8 antagonists identified from a high-throughput screen. These analogues exhibit good potency in binding and chemotaxis assays, show good selectivity versus the hERG channel, and have good eADME (early absorption, distribution, metabolism, and excretion) profiles.