1903-90-8

Basic information

• Product Name: 6-Hydroxy-2-(methoxymethyl)-4(3H)-pyrimidinone
• Synonyms: 2-Methoxymethylpyrimidine-4,6-diol;6-Hydroxy-2-(methoxymethyl)-4(3H)-pyrimidinone
• CAS NO: 1903-90-8
• Molecular Formula: C6H8N2O3
• Molecular Weight: 156
• Mol File: 1903-90-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 210℃ (DEC.)
• Appearance: /
• Density: 1.41
• PKA: 4.83±0.10(Predicted)
• CAS DataBase Reference: 6-Hydroxy-2-(methoxymethyl)-4(3H)-pyrimidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Hydroxy-2-(methoxymethyl)-4(3H)-pyrimidinone(1903-90-8)
• EPA Substance Registry System: 6-Hydroxy-2-(methoxymethyl)-4(3H)-pyrimidinone(1903-90-8)

Safety Data

• Hazardous Substances Data: 1903-90-8(Hazardous Substances Data)

Upstream product

• 3122-73-4 2-methoxyacetamidine 
• 105-53-3 diethyl malonate 
• 3938-96-3 ethyl 2-methoxyacetate 
• 108-13-4 malonodiamide 
• 1903-91-9 2-methoxyethanimidamide hydrochloride 

Downstream Products

• 1903-92-0 4,6-dichloro-2-(methoxymethyl)pyrimidine 
• 1044641-84-0 2-bromomethyl-4-(3-chloro-phenyl)-6-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-pyrimidine 
• 833463-32-4 4-(3-chloro-phenyl)-2-methoxymethyl-6-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-pyrimidine 

Relevant articles and documents

Compounds as syk kinase inhibitors

The present invention relates to a compound of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by inhibition of Syk kinase.

A COMBINATION OF NIACIN AND A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST

The present invention is directed to a pharmaceutical composition comprising Niacin or a pharmaceutically acceptable salt, solvate or N-oxide thereof, or a nicotinic acid receptor agonist, and a compound of formula (I) as defined herein, or an N-oxide thereof, or an ester prodrug thereof, or a pharmaceutically acceptable salt, hydrate, or solvate thereof, and its use for treating atherosclerosis, dyslipidemia, diabetes or a related condition while reducing substantial flushing.

Substituted N-[pyrimidin-2-ylmethyl]carboxamides and their use as herbicides and plant growth regulators

What is described are N-[pyrimidin-2-ylmethyl]carboxamides of the formula (I) and their use as herbicides. In this formula (I), X1 and X2 are hydrogen or methyl, R1 to R4 are various radicals and A is an aromati