190328-71-3Relevant articles and documents
Solvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity
Pessoa-Mahana, Hernan,Kosche C., Johann,Ron H., Nadia,Recabarren-Gajardo, Gonzalo,Saitz B., Claudio,Araya-Maturana, Ramiro,Pessoa-Mahana, C. David
experimental part, p. 1913 - 1929 (2009/04/06)
A novel series of 2-benzothiophenealkylpiperazine derivatives 11 (a-d) with potential affinity at 5-HT1A serotonin receptors have been synthesized via solvent-free, microwave-promoted Michael addition of benzo[b]thiophene piperazine derivatives 6(a-c) to substituted benzo[b]thiophen-2-yl propenones 10(b,c).
Synthesis of benzo[b]thiophene carboxamides connected to 4-arylpiperazines through a benzylic spacer: Potential ligands with 5-HT1A binding affinity
Pessoa-Mahana, Hernan,Acevedo,Araya-Maturana, Ramiro,Saitz, Claudio,Pessoa-Mahana, C. David
, p. 3559 - 3567 (2008/03/13)
New benzothiophene arylpiperazine derivatives 8 (a-f) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by treating N-[2-(chloromethyl)phenyl]-4,7- dimethoxybenzo[b]thiophene-2-
Studies on quinones: Part 30. Synthesis of benzo[b]thiophene-4,7- quinones
Valderrama, Jaime A.,Valderrama, Claudio
, p. 2143 - 2157 (2007/10/03)
The synthesis of a variety of benzo[b]thiophene-4,7-quinones (4a-f) by oxidative demethylation of the corresponding 4,7-dimethoxybenzo[b]thiophenes (3a-f) with cerium (IV) ammonium nitrate is reported. Heterocycles (3a,b) were prepared by cyclization of t
