19037-74-2Relevant articles and documents
Preparation of bis-quaternary ammonium salts from epichlorohydrin
Kim, Tae-Seong,Hirao, Toshikazu,Ikeda, Isao
, p. 67 - 71 (1996)
A novel bis-quaternary ammonium salt was prepared conveniently and almost quantitatively from N,N-dimethyldodecylamine, its hydrochloride, and epichlorohydrin. Reaction of N,N-dimethyldodecylamine with epichlorohydrin (in the presence of the amine hydrochloride) or various dichloro compounds was investigated by using 1H nuclear magnetic resonance. The reaction route was studied by examining the reactivity of reagents with the amine and the effect of reaction temperature. The ease of the reaction with epichlorohydrin was found to be due to the assistance of amine hydrochloride in opening the epoxide ring and to neighboring-group participation by the hydroxyl group of the intermediate mono-ammonium salt in the quaternization step. Neighboring-group participation by the hydroxyl group in these quaternization reactions is also discussed.
Method for preparing diethyl ether-alpha, omega-double long-chain alkyl dimethyl ammonium chloride surfactant
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Paragraph 0041-0043; 0050-0052, (2019/01/21)
The invention relates to a method for preparing a diethyl ether-alpha, omega-double long-chain alkyl dimethyl ammonium chloride surfactant. A solvent and a basic catalyst are added to a reactor, dichloroethyl ether is added to a dropping funnel, when the dropping temperature is reached, the dichloroethyl ether is added dropwise to the reactor, the reaction is carried out under stirring condition to obtain the product diethyl ether-alpha, omega-double long-chain alkyl dimethyl ammonium chloride surfactant, the obtained liquid product is evaporated to remove the solvent, washed with diethyl ether, and then vacuum dried with acetone to obtain a product. The method has the advantages of short reaction time and high yield.
