112-18-5

Usage

Uses

Used in Chemical Intermediates:
N,N-Dimethyldodecylamine is used as a chemical intermediate for the manufacture of quaternary ammonium compounds, amine oxide, and betaine surfactants. These compounds are essential in the production of cleaning agents and cosmetics.
Used in Synthesis of Bimetallic Nanoparticles:
N,N-Dimethyldodecylamine acts as a capping agent during the synthesis of Au(core)-Pd(shell) bimetallic nanoparticles in toluene. This application is crucial in the development of advanced materials with unique properties for various industries.
Used in the Synthesis of N-alkyl-N,N-dimethyl-1-ammonio-2-hydroxy-3-propane Sulfate:
N,N-Dimethyldodecylamine is also utilized in the synthesis of N-alkyl-N,N-dimethyl-1-ammonio-2-hydroxy-3-propane sulfate, which is an important ingredient in the formulation of cleaning agents and personal care products.
Used in the Preparation of Novel Bis-quaternary Ammonium Salt:
N,N-Dimethyldodecylamine is employed in the preparation of novel bis-quaternary ammonium salt, which has potential applications in various industries, including pharmaceuticals, agriculture, and water treatment.

Reactivity Profile

N,N-dimethyldodecylamine, a tertiary alkyl amine, is non-flammable but combustible (flash point >230°F). May react with copper and copper-containing alloys such as brass. Incompatible with strong oxidizing agents and with strong acids. Very toxic to the aquatic organisms. Dangerous to the environment.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

InChI:InChI=1/C14H31N.BrH/c1-4-5-6-7-8-9-10-11-12-13-14-15(2)3;/h4-14H2,1-3H3;1H

Upstream product

• 50-00-0 formaldehyd 
• 64-18-6 formic acid 
• 124-22-1 n-Dodecylamine 
• 143-15-7 1-dodecylbromide 
• 124-40-3 dimethyl amine 
• 112-53-8 1-dodecyl alcohol 
• 4292-19-7 1-Iodododecane 
• 2437-25-4 undecyl cyanide 
• 74-89-5 methylamine 
• 67-56-1 methanol 
• 74-83-9 methyl bromide 
• 7311-30-0 N-methyldodecylamine 
• 3007-53-2 N,N-dimethyldodecanamide 
• 112-52-7 1-chlorododecane 

Downstream Products

• 15687-13-5 [2-(4-chloro-phenoxy)-ethyl]-dodecyl-dimethyl-ammonium; bromide 
• 29811-96-9 [2-(2-chloro-phenoxy)-ethyl]-dodecyl-dimethyl-ammonium; bromide 
• 112-00-5 trimethyldodecylammonium chloride 
• 85909-51-9 benzyl-dodecyl-dimethyl-ammonium; thiocyanate 
• 90730-03-3 N-(ω-benzyloxyethyl)-N-dodecyl-N,N-dimethylammonium chloride 
• 4728-59-0 dodecyl-(2-hydroxy-3-phenoxy-propyl)-dimethyl-ammonium; chloride 
• 71242-01-8 [(benzyl-methyl-carbamoyl)-methyl]-dodecyl-dimethyl-ammonium; chloride 
• 683-10-3 carboxymethyl-dodecyl-dimethyl-ammonium betaine 
• 1643-20-5 dodecyl-N,N-dimethylamine N-oxide 
• 36211-32-2 dodecyl-dimethyl-(2,4,6-trimethyl-benzyl)-ammonium; chloride 
• 39923-13-2 dodecyl-dimethyl-(4-nitro-benzyl)-ammonium; chloride 

Related news

Dispersity of stratum corneum in the mixed aqueous solutions of binary mixtures between N,N-Dimethyldodecylamine (cas 112-18-5) oxide and sodium dodecyl sulfate or two terpenes08/29/2019

Solubilization of cholesterol, differential scanning calorimetric (DSC), nuclear magnetic resonance (NMR) and dynamic light scattering (DLS) measurements were performed in order to reveal the dispersion mechanisms of stratum corneum (SC) into each intact corneocytes in the following systems: (1)...detailed

Dispersion of stratum corneum in aqueous mixed solutions of surfactant and terpene: the effect of mixtures of N,N-Dimethyldodecylamine (cas 112-18-5) oxide and α-Terpineol08/28/2019

The dispersion of stratum corneum (SC) into intact cells has been studied in aqueous mixed micelle solutions containing α-Terpineol (α-T) solubilized in solutions of N,N-dimethyldodecylamine oxide (C12,DMAO). The dispersion was found to be most effective when α-T is solubilized in the saturat...detailed

The solubilization of limonene in aqueous micellar solution of N,N-Dimethyldodecylamine (cas 112-18-5) oxide and dispersity of stratum corneum in the solution08/27/2019

The dispersion of stratum corneum (SC) into each intact cell was studied in aqueous micellar solutions of N,N-dimethyldodecylamine oxide (C12DMAO) solubilizing limonene and was found to be the most effective, especially when the saturated amount of limonene was solubilized in the micellar soluti...detailed

Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-Dimethyldodecylamine (cas 112-18-5) N-oxide aqueous systems performed at low temperatures08/22/2019

Surfactant crystallisation is important in many applications in the food, consumer product and medical sectors. However, these processes are not well understood. In particular, surfactant crystallisation can be detrimental to the stability of detergent formulations, such as dish liquid products,...detailed

Regular ArticleThe impact of N,N-Dimethyldodecylamine (cas 112-18-5) N-oxide (DDAO) concentration on the crystallisation of sodium dodecyl sulfate (SDS) systems and the resulting changes to crystal structure, shape and the kinetics of crystal growth08/21/2019

HypothesisAt low temperatures stability issues arise in commercial detergent products when surfactant crystallisation occurs, a process which is not currently well-understood. An understanding of the phase transition can be obtained using a simple binary SDS (sodium dodecyl sulfate) + DDAO (N,N-...detailed

Fabrication of N,N-Dimethyldodecylamine (cas 112-18-5) functionalized magnetic adsorbent for efficient enrichment of flavonoids08/20/2019

A new N,N-dimethyldodecylamine functionalized magnetic adsorbent (Fe3O4@MDHM) was fabricated and used for the efficient enrichment of flavonoids under the format of magnetic solid phase extraction (MSPE). Different techniques were utilized to characterize the spectroscopic, morphology and magnet...detailed

Relevant academic research and scientific papers

Synthesis and properties of biodegradable cationic gemini surfactants with diester and flexible spacers

A series of cationic gemini surfactants with diester and flexible spacers, namely C12-PG-C12, C14-PG-C14 and C16-PG-C16, were synthesized, purified and characterized. The surface properties and aggregation behavior of the gemini surfactants were investigated by surface tension, electrical conductivity, fluorescence and Krafft point. These gemini surfactants possess higher surface activity than the traditional monomeric surfactants. The thermodynamic parameters exhibited that the micellization was a spontaneous and exothermic process in environment. The micellization process became less favorable with the decrease of alkyl chain length and the increase of temperature. Steady-state fluorescence measurements revealed that the micropolarity and aggregation number of micelles decreased with the increase of hydrocarbon chain length. The Krafft points were taken as ?0?°C, which indicated the synthesized gemini surfactants had good water solubility. The biodegradability of the gemini surfactants were evaluated in river water using Closed Bottle tested and showed their high biodegradation ratio in the open environment due to the diester bond inserting in the flexible spacer of surfactant molecules.

Micellization of cationic gemini surfactants with various counterions and their interaction with DNA in aqueous solution

The micellization of six cationic gemini surfactants with various counterions, [C12H25(CH3)2N(CH 2)6N(CH3)2C12H 25]X2, designated as C12C6C 12X2 with X = F-, Cl-, Br -, Ac-, NO3-, and 1/2SO 42- in aqueous solutions has been investigated by isothermal titration microcalorimetry (ITC) and conductivity measurements. The interaction of these surfactants with DNA in aqueous solutions has also been investigated by isothermal titration microcalorimetry. The critical micelle concentration (CMC) and the degree of micellar ionization (?±), the critical aggregation concentration (CAC), the saturation concentration (C 2) of the aggregation, and the associated thermodynamic parameters were determined. The nature of the counterion significantly affects the processes of both micellization and aggregation. The trends for aggregation basically follow the Hofmeister (lyotropic) series, but the pattern of the variation of the enthalpy of aggregation often revealed a more complex behavior. Among the counterions examined, SO42- is the most effective anion for decreasing the CMC (or CAC). Both aggregation processes are mainly entropy-driven since the values of the entropy changes multiplied by temperature are much larger than the absolute values of the enthalpy changes. The binding of micelles to DNA is strongly dominated by the positive entropy gain on release of the small counterions from the micelles and from DNA. The interaction of all of the surfactants with DNA was dependent on the DNA concentration and may be associated with each micelle interacting with more than one DNA molecule.

Chemical synthesis of silver nanowires using N,N-dimethyldodecylamine oxide

This paper describes a new approach for the synthesis of uniform silver nanowires (AgNWs) using zwitterionic amphiphile, N,N-dimethyldodecylamine oxide (DDAO). Heating of AgCl and DDAO in the presence of silver nanoparticles at 135°C for 3 h produces longer AgNWs. The DDAO serves as a source of both a reducing and capping agent in the process.

Modeling of the hydrophobic microenvironment of water-soluble molybdoenzymes in an aqueous micellar solution

A toluene-soluble molybdenum(vi) complex containing a bulky hydrophobic substituent, (Et4N)2[MoVIO2{1,2-S2-3,6-(RCONH)2C6H2}2] (R = (4-tBuC6H4)3C), was dissolved in the hydrophobic core of a micelle in an aqueous medium and catalyzed the biomimetic reduction of an amine N-oxide by an NADH analog. The kinetic isotope effect of solvent water clearly indicates that water molecules are essential for catalysis and are involved in the rate-determining step.

PROCESS FOR CONVERTING AMIDE TO AMINE

Provided is a process for converting an amide into an amine comprising hydrogenation of the amide at a temperature not higher than 130°C and a hydrogen pressure not higher than 50 bar in the presence of a supported heterogeneous catalyst preparable by a method comprising depositing vanadium on a supported noble metal catalyst by impregnation.

SUPPORTED HETEROGENEOUS CATALYST, PREPARATION AND USE THEREOF

A supported heterogeneous catalyst comprises rhodium and vanadium on a support, wherein the supported heterogeneous catalyst is preparable by depositing vanadium on a supported rhodium catalyst by impregnation. A process for preparing the aforementioned catalyst and a process for converting an amide into an amine in the presence of the aforementioned catalyst are provided.

Efficient hydrogenation of aliphatic amides to amines over vanadium-modified rhodium supported catalyst

This work presents a highly efficient catalytic hydrogenation system developed for the selective transformation of tertiary N,N-dimethyldodecanamide and secondary azepan-2-one amides to the corresponding amines. Industrial hydrogenation catalysts Pd/Al2O3, Pt/Al2O3 and Rh/Al2O3 were modified with vanadium (V) or molybdenum (Mo) species as oxophilic centres. The modified catalysts were prepared by deposition of V or Mo precursor on supported catalysts via impregnation method. The catalysts were characterized by ICP-OES, XRD, XPS, H2-TPR, FTIR, CO-chemisorption, TEM, SEM-EDX and TGA. Modified Rh-V/Al2O3 catalyst displayed the best performance affording high yield and selectivity >95 % to the desired tertiary and secondary amines at moderate reaction conditions of T H2 0 sites and oxophilic Vδ+ sites in the bimetallic Rh-V/Al2O3 catalyst were determined to be beneficial for the selective dissociation of C[dbnd]O bond of the carboxamides into the desired amines.

Method for realizing N-alkylation by using alcohols as carbon source under photocatalysis

The invention discloses a method for realizing N-alkylation by using alcohols as a carbon source under photocatalysis, and belongs to the technical field of catalytic synthesis. Alcohol, a substrate raw material and a catalyst are placed in a reaction device, ultraviolet and/or visible light irradiation is carried out in an inert atmosphere, after the irradiation is finished, solid-liquid separation is carried out to remove the catalyst, and an N-alkylation product can be obtained through extraction, distillation and purification, wherein the substrate raw material comprises any one of an amine compound, an aromatic nitro compound or an aromatic nitrile compound, the alcohol comprises any one or more of soluble primary alcohols, and the catalyst is metal oxide/titanium dioxide or metal sulfide/titanium dioxide. The method is simple and easy to operate, can be used for efficient photocatalysis one-pot multi-step hydrogenation N-alkylation reaction, and is mild in reaction condition, high in chemical selectivity of N-alkylamine, good in catalyst stability and easy to recycle.

N-Methylation of amines and nitroarenes with methanol using heterogeneous platinum catalysts

We report herein the selective N-methylation of amines and nitroarenes with methanol under basic conditions using carbon-supported Pt nanoparticles (Pt/C) as a heterogeneous catalyst. This method is widely applicable to four types of N-methylation reactions: (1) N,N-dimethylation of aliphatic amines under N2, (2) N-monomethylation of aliphatic amines under 40 bar H2, (3) N-monomethylation of aromatic amines under N2, and (4) tandem synthesis of N-methyl anilines from nitroarenes and methanol under 2 bar H2. All these reactions under the same catalytic system showed high yields of the corresponding methylamines for a wide range of substrates, high turnover number (TON), and good catalyst reusability. Mechanistic studies suggested that the reaction proceeded via a borrowing hydrogen methodology. Kinetic results combined with density functional theory (DFT) calculations revealed that the high performance of Pt/C was ascribed to the moderate metal–hydrogen bond strength of Pt.

Cationic linear chloramine antibacterial agent and synthesis method thereof

The invention belongs to the technical field of synthesis and application of chloramine antibacterial agents, and provides a synthesis method of a cationic linear chloramine antibacterial agent. N-tert-butyl-chloroalkylamide II and a compound IV are used as raw materials to prepare a chloramine precursor compound III, then to be reacted with tert-butyl hypochlorite at a room temperature to preparea chloramine compound I; and the compound IV is one of a tertiary amine compound IV1 with different alkyl chains, a pyridine compound IV2 with different alkyl chains and tributyl phosphine. Accordingto the preparation method, when use of potassium cyanide is avoided, different cation structures are introduced into linear chloramine molecules to improve water solubility and improve the antibacterial activity; moreover, the structure of long alkyl chains and the chloramine structure introduced into the cation center can produce the strong synergistic antibacterial effect, and the antibacterialactivity is significantly improved compared with hydantoin like chloramine; and the theoretical basis is hopefully provided for preparation of high-efficiency cationic chloramine antibacterial materials .