112-18-5

Basic information

• Product Name: N,N-Dimethyldodecylamine
• Synonyms: 1,1-Dimethyl-aminododecane;1-Dodecanamine,N,N-dimethyl-;Adma 2;Adma12;adma2;Amine 2M12D;Antioxidant DDA;antioxidantdda
• CAS NO: 112-18-5
• Molecular Formula: C₁₄H₃₁N
• Molecular Weight: 213.4
• EINECS: 203-943-8
• Product Categories: Pyridines
• Mol File: 112-18-5.mol
• Article Data: 54

Chemical Properties

• Melting Point: −20 °C(lit.)
• Boiling Point: 80-82 °C0.1 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear/Liquid
• Density: 0.787 g/mL at 20 °C(lit.)
• Vapor Pressure: <129 mm Hg ( 21 °C)
• Refractive Index: n20/D 1.4375(lit.)
• Storage Temp.: -20°C
• PKA: 9.78±0.28(Predicted)
• Water Solubility: Negligible
• Sensitive: Air & Moisture Sensitive
• BRN: 1700191
• CAS DataBase Reference: N,N-Dimethyldodecylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dimethyldodecylamine(112-18-5)
• EPA Substance Registry System: N,N-Dimethyldodecylamine(112-18-5)

Safety Data

• Hazard Codes: C,N
• Statements: 22-34-50/53
• Safety Statements: 26-36/37/39-45-60-61
• RIDADR: UN 2735 8/PG 2
• WGK Germany: 2
• RTECS: JR6600000
• F: 10-34
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 112-18-5(Hazardous Substances Data)

Usage

Chemical Properties

Liquid

Uses

Different sources of media describe the Uses of 112-18-5 differently. You can refer to the following data:
1. Barlene(R) tertiary amines are used as chemical intermediates for the manufacture of quaternary ammonium compounds, amine oxide and betaine surfactants
2. N,N-Dimethyldodecylamine is used as a as a capping agent during the synthesis of Au(core) -Pd(shell) bimetallic nanoparticles in toluene. It is used in the synthesis of N-alkyl-N,N-dimethyl-1-ammonio-2-hydroxy-3-propane sulfonate. Also used in the preparation of novel bis-quaternary ammonium salt.

General Description

N,N-Dimethyldodecylamine is a colorless to light colored liquid at room temperature. Has the fishy odor that characterizes fatty amines. Very slightly soluble in water and denser than water. Industrial materials containing this compound typically are blends with closely similar alkyl compounds such as tetradecyldimethylamine and hexadecyldimethylamine. Used as intermediates in the manufacture of quaternary ammonium compounds for use in cleaning agents and cosmetics.

Reactivity Profile

N,N-dimethyldodecylamine, a tertiary alkyl amine, is non-flammable but combustible (flash point >230°F). May react with copper and copper-containing alloys such as brass. Incompatible with strong oxidizing agents and with strong acids. Very toxic to the aquatic organisms. Dangerous to the environment.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

InChI:InChI=1/C14H31N.BrH/c1-4-5-6-7-8-9-10-11-12-13-14-15(2)3;/h4-14H2,1-3H3;1H

Upstream product

• 50-00-0 formaldehyd 
• 64-18-6 formic acid 
• 124-22-1 n-Dodecylamine 
• 143-15-7 1-dodecylbromide 
• 124-40-3 dimethyl amine 
• 112-53-8 1-dodecyl alcohol 
• 4292-19-7 1-Iodododecane 
• 112-52-7 1-chlorododecane 
• 75-50-3 trimethylamine 
• 67-56-1 methanol 
• 74-83-9 methyl bromide 
• 7311-30-0 N-methyldodecylamine 
• 3007-53-2 N,N-dimethyldodecanamide 
• 143-07-7 lauric acid 

Downstream Products

• 97221-97-1 2-chloro-benzoic acid dodecyl ester 
• 15687-13-5 [2-(4-chloro-phenoxy)-ethyl]-dodecyl-dimethyl-ammonium; bromide 
• 29811-96-9 [2-(2-chloro-phenoxy)-ethyl]-dodecyl-dimethyl-ammonium; bromide 
• 112-00-5 trimethyldodecylammonium chloride 
• 36211-32-2 dodecyl-dimethyl-(2,4,6-trimethyl-benzyl)-ammonium; chloride 
• 39923-13-2 dodecyl-dimethyl-(4-nitro-benzyl)-ammonium; chloride 
• 683-10-3 carboxymethyl-dodecyl-dimethyl-ammonium betaine 
• 31978-07-1 (dimethyl)(dodecyl)allylammonium chloride 
• 1733-96-6 N-dodecyl-N,N-dimethyl-N-(1naphthylmethyl)ammonium chloride 
• 15538-15-5 carbamoylmethyl-dodecyl-dimethyl-ammonium; chloride 
• 14933-08-5 N-dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate 
• 82820-57-3 Toluene-4-sulfonateN-dodecyl-N,N,N'-trimethyl-hydrazinium; 
• 103683-18-7 C₂₁H₄₄N₂O₄S 
• 103683-20-1 C₂₂H₄₆N₂O₄S 

Related news

Dispersity of stratum corneum in the mixed aqueous solutions of binary mixtures between N,N-Dimethyldodecylamine (cas 112-18-5) oxide and sodium dodecyl sulfate or two terpenes08/29/2019

Solubilization of cholesterol, differential scanning calorimetric (DSC), nuclear magnetic resonance (NMR) and dynamic light scattering (DLS) measurements were performed in order to reveal the dispersion mechanisms of stratum corneum (SC) into each intact corneocytes in the following systems: (1)...detailed

Dispersion of stratum corneum in aqueous mixed solutions of surfactant and terpene: the effect of mixtures of N,N-Dimethyldodecylamine (cas 112-18-5) oxide and α-Terpineol08/28/2019

The dispersion of stratum corneum (SC) into intact cells has been studied in aqueous mixed micelle solutions containing α-Terpineol (α-T) solubilized in solutions of N,N-dimethyldodecylamine oxide (C12,DMAO). The dispersion was found to be most effective when α-T is solubilized in the saturat...detailed

The solubilization of limonene in aqueous micellar solution of N,N-Dimethyldodecylamine (cas 112-18-5) oxide and dispersity of stratum corneum in the solution08/27/2019

The dispersion of stratum corneum (SC) into each intact cell was studied in aqueous micellar solutions of N,N-dimethyldodecylamine oxide (C12DMAO) solubilizing limonene and was found to be the most effective, especially when the saturated amount of limonene was solubilized in the micellar soluti...detailed

Nuclear magnetic resonance and small-angle X-ray scattering studies of mixed sodium dodecyl sulfate and N,N-Dimethyldodecylamine (cas 112-18-5) N-oxide aqueous systems performed at low temperatures08/22/2019

Surfactant crystallisation is important in many applications in the food, consumer product and medical sectors. However, these processes are not well understood. In particular, surfactant crystallisation can be detrimental to the stability of detergent formulations, such as dish liquid products,...detailed

Regular ArticleThe impact of N,N-Dimethyldodecylamine (cas 112-18-5) N-oxide (DDAO) concentration on the crystallisation of sodium dodecyl sulfate (SDS) systems and the resulting changes to crystal structure, shape and the kinetics of crystal growth08/21/2019

HypothesisAt low temperatures stability issues arise in commercial detergent products when surfactant crystallisation occurs, a process which is not currently well-understood. An understanding of the phase transition can be obtained using a simple binary SDS (sodium dodecyl sulfate) + DDAO (N,N-...detailed

Fabrication of N,N-Dimethyldodecylamine (cas 112-18-5) functionalized magnetic adsorbent for efficient enrichment of flavonoids08/20/2019

A new N,N-dimethyldodecylamine functionalized magnetic adsorbent (Fe3O4@MDHM) was fabricated and used for the efficient enrichment of flavonoids under the format of magnetic solid phase extraction (MSPE). Different techniques were utilized to characterize the spectroscopic, morphology and magnet...detailed

Relevant articles and documents

Synthesis and properties of biodegradable cationic gemini surfactants with diester and flexible spacers

A series of cationic gemini surfactants with diester and flexible spacers, namely C12-PG-C12, C14-PG-C14 and C16-PG-C16, were synthesized, purified and characterized. The surface properties and aggregation behavior of the gemini surfactants were investigated by surface tension, electrical conductivity, fluorescence and Krafft point. These gemini surfactants possess higher surface activity than the traditional monomeric surfactants. The thermodynamic parameters exhibited that the micellization was a spontaneous and exothermic process in environment. The micellization process became less favorable with the decrease of alkyl chain length and the increase of temperature. Steady-state fluorescence measurements revealed that the micropolarity and aggregation number of micelles decreased with the increase of hydrocarbon chain length. The Krafft points were taken as ?0?°C, which indicated the synthesized gemini surfactants had good water solubility. The biodegradability of the gemini surfactants were evaluated in river water using Closed Bottle tested and showed their high biodegradation ratio in the open environment due to the diester bond inserting in the flexible spacer of surfactant molecules.

Chemical synthesis of silver nanowires using N,N-dimethyldodecylamine oxide

This paper describes a new approach for the synthesis of uniform silver nanowires (AgNWs) using zwitterionic amphiphile, N,N-dimethyldodecylamine oxide (DDAO). Heating of AgCl and DDAO in the presence of silver nanoparticles at 135°C for 3 h produces longer AgNWs. The DDAO serves as a source of both a reducing and capping agent in the process.

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PROCESS FOR CONVERTING AMIDE TO AMINE

Provided is a process for converting an amide into an amine comprising hydrogenation of the amide at a temperature not higher than 130°C and a hydrogen pressure not higher than 50 bar in the presence of a supported heterogeneous catalyst preparable by a method comprising depositing vanadium on a supported noble metal catalyst by impregnation.

Efficient hydrogenation of aliphatic amides to amines over vanadium-modified rhodium supported catalyst

This work presents a highly efficient catalytic hydrogenation system developed for the selective transformation of tertiary N,N-dimethyldodecanamide and secondary azepan-2-one amides to the corresponding amines. Industrial hydrogenation catalysts Pd/Al2O3, Pt/Al2O3 and Rh/Al2O3 were modified with vanadium (V) or molybdenum (Mo) species as oxophilic centres. The modified catalysts were prepared by deposition of V or Mo precursor on supported catalysts via impregnation method. The catalysts were characterized by ICP-OES, XRD, XPS, H2-TPR, FTIR, CO-chemisorption, TEM, SEM-EDX and TGA. Modified Rh-V/Al2O3 catalyst displayed the best performance affording high yield and selectivity >95 % to the desired tertiary and secondary amines at moderate reaction conditions of T H2 0 sites and oxophilic Vδ+ sites in the bimetallic Rh-V/Al2O3 catalyst were determined to be beneficial for the selective dissociation of C[dbnd]O bond of the carboxamides into the desired amines.